Chen H - Search Results

1

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes.

Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY. Chao HT, et al. Among authors: chen h. Nature. 2010 Nov 11;468(7321):263-9. doi: 10.1038/nature09582. Nature. 2010. PMID: 21068835 Free PMC article.

2

Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system.

Xue M, Stradomska A, Chen H, Brose N, Zhang W, Rosenmund C, Reim K. Xue M, et al. Among authors: chen h. Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7875-80. doi: 10.1073/pnas.0803012105. Epub 2008 May 27. Proc Natl Acad Sci U S A. 2008. PMID: 18505837 Free PMC article.

3

GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination.

Wu CS, Chen H, Sun H, Zhu J, Jew CP, Wager-Miller J, Straiker A, Spencer C, Bradshaw H, Mackie K, Lu HC. Wu CS, et al. Among authors: chen h. PLoS One. 2013;8(4):e60314. doi: 10.1371/journal.pone.0060314. Epub 2013 Apr 2. PLoS One. 2013. PMID: 23565223 Free PMC article.

4

SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties.

Han K, Holder JL Jr, Schaaf CP, Lu H, Chen H, Kang H, Tang J, Wu Z, Hao S, Cheung SW, Yu P, Sun H, Breman AM, Patel A, Lu HC, Zoghbi HY. Han K, et al. Among authors: chen h. Nature. 2013 Nov 7;503(7474):72-7. doi: 10.1038/nature12630. Epub 2013 Oct 23. Nature. 2013. PMID: 24153177 Free PMC article.

5

Loss of MeCP2 in Parvalbumin-and Somatostatin-Expressing Neurons in Mice Leads to Distinct Rett Syndrome-like Phenotypes.

Ito-Ishida A, Ure K, Chen H, Swann JW, Zoghbi HY. Ito-Ishida A, et al. Among authors: chen h. Neuron. 2015 Nov 18;88(4):651-8. doi: 10.1016/j.neuron.2015.10.029. Neuron. 2015. PMID: 26590342 Free PMC article.

6

Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligonucleotides.

Sztainberg Y, Chen HM, Swann JW, Hao S, Tang B, Wu Z, Tang J, Wan YW, Liu Z, Rigo F, Zoghbi HY. Sztainberg Y, et al. Nature. 2015 Dec 3;528(7580):123-6. doi: 10.1038/nature16159. Epub 2015 Nov 25. Nature. 2015. PMID: 26605526 Free PMC article.

7

Targeting light-gated chloride channels to neuronal somatodendritic domain reduces their excitatory effect in the axon.

Messier JE, Chen H, Cai ZL, Xue M. Messier JE, et al. Among authors: chen h. Elife. 2018 Aug 9;7:e38506. doi: 10.7554/eLife.38506. Elife. 2018. PMID: 30091701 Free PMC article.

8

Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy.

Chen W, Cai ZL, Chao ES, Chen H, Longley CM, Hao S, Chao HT, Kim JH, Messier JE, Zoghbi HY, Tang J, Swann JW, Xue M. Chen W, et al. Among authors: chen h. Elife. 2020 Feb 19;9:e48705. doi: 10.7554/eLife.48705. Elife. 2020. PMID: 32073399 Free PMC article.

9

GABAergic/Glycinergic and Glutamatergic Neurons Mediate Distinct Neurodevelopmental Phenotypes of STXBP1 Encephalopathy.

Kim JH, Chen W, Chao ES, Rivera A, Kaku HN, Jiang K, Lee D, Chen H, Vega JM, Chin TV, Jin K, Nguyen KT, Zou SS, Moin Z, Nguyen S, Xue 薛名杉 M. Kim JH, et al. Among authors: chen w, chen h. J Neurosci. 2024 Apr 3;44(14):e1806232024. doi: 10.1523/JNEUROSCI.1806-23.2024. J Neurosci. 2024. PMID: 38360746 Free PMC article.

10

Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission.

Weston MC, Chen H, Swann JW. Weston MC, et al. Among authors: chen h. J Neurosci. 2012 Aug 15;32(33):11441-52. doi: 10.1523/JNEUROSCI.1283-12.2012. J Neurosci. 2012. PMID: 22895726 Free PMC article.

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