Al-Husein B - Search Results

1

PI3 kinase integrates Akt and MAP kinase signaling pathways in the regulation of prostate cancer.

Goc A, Al-Husein B, Kochuparambil ST, Liu J, Heston WW, Somanath PR. Goc A, et al. Int J Oncol. 2011 Jan;38(1):267-77. Int J Oncol. 2011. PMID: 21109949

2

Anticancer efficacy of simvastatin on prostate cancer cells and tumor xenografts is associated with inhibition of Akt and reduced prostate-specific antigen expression.

Kochuparambil ST, Al-Husein B, Goc A, Soliman S, Somanath PR. Kochuparambil ST, et al. J Pharmacol Exp Ther. 2011 Feb;336(2):496-505. doi: 10.1124/jpet.110.174870. Epub 2010 Nov 8. J Pharmacol Exp Ther. 2011. PMID: 21059805

3

Simultaneous modulation of the intrinsic and extrinsic pathways by simvastatin in mediating prostate cancer cell apoptosis.

Goc A, Kochuparambil ST, Al-Husein B, Al-Azayzih A, Mohammad S, Somanath PR. Goc A, et al. BMC Cancer. 2012 Sep 14;12:409. doi: 10.1186/1471-2407-12-409. BMC Cancer. 2012. PMID: 22974127 Free PMC article.

4

P21 activated kinase-1 (Pak1) promotes prostate tumor growth and microinvasion via inhibition of transforming growth factor β expression and enhanced matrix metalloproteinase 9 secretion.

Goc A, Al-Azayzih A, Abdalla M, Al-Husein B, Kavuri S, Lee J, Moses K, Somanath PR. Goc A, et al. J Biol Chem. 2013 Feb 1;288(5):3025-35. doi: 10.1074/jbc.M112.424770. Epub 2012 Dec 20. J Biol Chem. 2013. PMID: 23258534 Free PMC article.

5

Suppression of interactions between prostate tumor cell-surface integrin and endothelial ICAM-1 by simvastatin inhibits micrometastasis.

Al-Husein B, Goc A, Somanath PR. Al-Husein B, et al. J Cell Physiol. 2013 Nov;228(11):2139-48. doi: 10.1002/jcp.24381. J Cell Physiol. 2013. PMID: 23559257 Free PMC article.

6

Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo.

Goc A, Al-Husein B, Katsanevas K, Steinbach A, Lou U, Sabbineni H, DeRemer DL, Somanath PR. Goc A, et al. Oncotarget. 2014 Feb 15;5(3):775-87. doi: 10.18632/oncotarget.1770. Oncotarget. 2014. PMID: 24519956 Free PMC article.

7

Antiangiogenic therapy for cancer: an update.

Al-Husein B, Abdalla M, Trepte M, Deremer DL, Somanath PR. Al-Husein B, et al. Pharmacotherapy. 2012 Dec;32(12):1095-111. doi: 10.1002/phar.1147. Pharmacotherapy. 2012. PMID: 23208836 Free PMC article. Review.

8

PAK1 as a therapeutic target.

Kichina JV, Goc A, Al-Husein B, Somanath PR, Kandel ES. Kichina JV, et al. Expert Opin Ther Targets. 2010 Jul;14(7):703-25. doi: 10.1517/14728222.2010.492779. Expert Opin Ther Targets. 2010. PMID: 20507214 Free PMC article. Review.

9

Diltiazem enhances the apoptotic effects of proteasome inhibitors to induce prostate cancer cell death.

Kaddour-Djebbar I, Choudhary V, Lakshmikanthan V, Shirley R, El Gaish M, Al-Shabrawey M, Al-Husein B, Zhong R, Davis M, Dong Z, Bollag WB, Kumar MV. Kaddour-Djebbar I, et al. J Pharmacol Exp Ther. 2012 Jun;341(3):646-55. doi: 10.1124/jpet.111.188151. Epub 2012 Mar 5. J Pharmacol Exp Ther. 2012. PMID: 22393247

10

Immunomodulatory effect of statins on Regulatory T Lymphocytes in human colorectal cancer is determined by the stage of disease.

Al-Husein BA, Dawah B, Bani-Hani S, Al Bashir SM, Al-Sawalmeh KM, Ayoub NM. Al-Husein BA, et al. Oncotarget. 2018 Nov 6;9(87):35752-35761. doi: 10.18632/oncotarget.26293. eCollection 2018 Nov 6. Oncotarget. 2018. PMID: 30515267 Free PMC article.

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