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Genetic proof for the transient nature of the Th17 phenotype.
Kurschus FC, Croxford AL, Heinen AP, Wörtge S, Ielo D, Waisman A. Kurschus FC, et al. Among authors: waisman a. Eur J Immunol. 2010 Dec;40(12):3336-46. doi: 10.1002/eji.201040755. Eur J Immunol. 2010. PMID: 21110317 Free article.
IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells.
Korn T, Mitsdoerffer M, Croxford AL, Awasthi A, Dardalhon VA, Galileos G, Vollmar P, Stritesky GL, Kaplan MH, Waisman A, Kuchroo VK, Oukka M. Korn T, et al. Among authors: waisman a. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18460-5. doi: 10.1073/pnas.0809850105. Epub 2008 Nov 17. Proc Natl Acad Sci U S A. 2008. PMID: 19015529 Free PMC article.
Cellular mechanisms of IL-17-induced blood-brain barrier disruption.
Huppert J, Closhen D, Croxford A, White R, Kulig P, Pietrowski E, Bechmann I, Becher B, Luhmann HJ, Waisman A, Kuhlmann CR. Huppert J, et al. Among authors: waisman a. FASEB J. 2010 Apr;24(4):1023-34. doi: 10.1096/fj.09-141978. Epub 2009 Nov 25. FASEB J. 2010. PMID: 19940258
These observations indicate that IL-17A accounts for a crucial step in the development of EAE by impairing the integrity of the BBB, involving augmented production of ROS.-Huppert, J., Closhen, D., Croxford, A., White, R., Kulig, P., Pietrowski, E., Bechmann, I., Be …
These observations indicate that IL-17A accounts for a crucial step in the development of EAE by impairing the integrity of the BBB, …
Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis.
Kleiter I, Song J, Lukas D, Hasan M, Neumann B, Croxford AL, Pedré X, Hövelmeyer N, Yogev N, Mildner A, Prinz M, Wiese E, Reifenberg K, Bittner S, Wiendl H, Steinman L, Becker C, Bogdahn U, Neurath MF, Steinbrecher A, Waisman A. Kleiter I, et al. Among authors: waisman a. Brain. 2010 Apr;133(Pt 4):1067-81. doi: 10.1093/brain/awq039. Epub 2010 Mar 30. Brain. 2010. PMID: 20354004 Free PMC article.
360 results