Felsher D - Search Results

1

TGFβ-dependent gene expression shows that senescence correlates with abortive differentiation along several lineages in Myc-induced lymphomas.

Müller J, Samans B, van Riggelen J, Fagà G, Peh K N R, Wei CL, Müller H, Amati B, Felsher D, Eilers M. Müller J, et al. Among authors: felsher d. Cell Cycle. 2010 Dec 1;9(23):4622-6. doi: 10.4161/cc.9.23.14211. Cell Cycle. 2010. PMID: 21127397

2

Myc and a Cdk2 senescence switch.

van Riggelen J, Felsher DW. van Riggelen J, et al. Nat Cell Biol. 2010 Jan;12(1):7-9. doi: 10.1038/ncb0110-7. Nat Cell Biol. 2010. PMID: 20027199

3

MYC as a regulator of ribosome biogenesis and protein synthesis.

van Riggelen J, Yetil A, Felsher DW. van Riggelen J, et al. Nat Rev Cancer. 2010 Apr;10(4):301-9. doi: 10.1038/nrc2819. Nat Rev Cancer. 2010. PMID: 20332779 Review.

4

The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance.

van Riggelen J, Müller J, Otto T, Beuger V, Yetil A, Choi PS, Kosan C, Möröy T, Felsher DW, Eilers M. van Riggelen J, et al. Genes Dev. 2010 Jun 15;24(12):1281-94. doi: 10.1101/gad.585710. Genes Dev. 2010. PMID: 20551174 Free PMC article.

5

MYC regulates the antitumor immune response through CD47 and PD-L1.

Casey SC, Tong L, Li Y, Do R, Walz S, Fitzgerald KN, Gouw AM, Baylot V, Gütgemann I, Eilers M, Felsher DW. Casey SC, et al. Science. 2016 Apr 8;352(6282):227-31. doi: 10.1126/science.aac9935. Epub 2016 Mar 10. Science. 2016. PMID: 26966191 Free PMC article.

6

Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation.

Wu CH, van Riggelen J, Yetil A, Fan AC, Bachireddy P, Felsher DW. Wu CH, et al. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13028-33. doi: 10.1073/pnas.0701953104. Epub 2007 Jul 30. Proc Natl Acad Sci U S A. 2007. PMID: 17664422 Free PMC article.

7

Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction.

Choi PS, van Riggelen J, Gentles AJ, Bachireddy P, Rakhra K, Adam SJ, Plevritis SK, Felsher DW. Choi PS, et al. Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17432-7. doi: 10.1073/pnas.1107303108. Epub 2011 Oct 3. Proc Natl Acad Sci U S A. 2011. PMID: 21969595 Free PMC article.

8

p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia.

Yetil A, Anchang B, Gouw AM, Adam SJ, Zabuawala T, Parameswaran R, van Riggelen J, Plevritis S, Felsher DW. Yetil A, et al. Oncotarget. 2015 Feb 28;6(6):3563-77. doi: 10.18632/oncotarget.2969. Oncotarget. 2015. PMID: 25784651 Free PMC article.

9

Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch.

Giuriato S, Ryeom S, Fan AC, Bachireddy P, Lynch RC, Rioth MJ, van Riggelen J, Kopelman AM, Passegué E, Tang F, Folkman J, Felsher DW. Giuriato S, et al. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16266-71. doi: 10.1073/pnas.0608017103. Epub 2006 Oct 20. Proc Natl Acad Sci U S A. 2006. PMID: 17056717 Free PMC article.

10

CDK2 is required by MYC to induce apoptosis.

Deb-Basu D, Aleem E, Kaldis P, Felsher DW. Deb-Basu D, et al. Among authors: felsher dw. Cell Cycle. 2006 Jun;5(12):1342-7. doi: 10.4161/cc.5.12.2859. Epub 2006 Jun 15. Cell Cycle. 2006. PMID: 16760655

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