de Laat W - Search Results

1

Genome organization influences partner selection for chromosomal rearrangements.

Wijchers PJ, de Laat W. Wijchers PJ, et al. Among authors: de laat w. Trends Genet. 2011 Feb;27(2):63-71. doi: 10.1016/j.tig.2010.11.001. Epub 2010 Dec 7. Trends Genet. 2011. PMID: 21144612 Review.

2

High-resolution identification of balanced and complex chromosomal rearrangements by 4C technology.

Simonis M, Klous P, Homminga I, Galjaard RJ, Rijkers EJ, Grosveld F, Meijerink JP, de Laat W. Simonis M, et al. Among authors: de laat w. Nat Methods. 2009 Nov;6(11):837-42. doi: 10.1038/nmeth.1391. Epub 2009 Oct 11. Nat Methods. 2009. PMID: 19820713

3

The complex transcription regulatory landscape of our genome: control in three dimensions.

Splinter E, de Laat W. Splinter E, et al. Among authors: de laat w. EMBO J. 2011 Sep 27;30(21):4345-55. doi: 10.1038/emboj.2011.344. EMBO J. 2011. PMID: 21952046 Free PMC article. Review.

4

A decade of 3C technologies: insights into nuclear organization.

de Wit E, de Laat W. de Wit E, et al. Among authors: de laat w. Genes Dev. 2012 Jan 1;26(1):11-24. doi: 10.1101/gad.179804.111. Genes Dev. 2012. PMID: 22215806 Free PMC article. Review.

5

eRNAs are required for p53-dependent enhancer activity and gene transcription.

Melo CA, Drost J, Wijchers PJ, van de Werken H, de Wit E, Oude Vrielink JA, Elkon R, Melo SA, Léveillé N, Kalluri R, de Laat W, Agami R. Melo CA, et al. Among authors: de laat w, de wit e. Mol Cell. 2013 Feb 7;49(3):524-35. doi: 10.1016/j.molcel.2012.11.021. Epub 2012 Dec 27. Mol Cell. 2013. PMID: 23273978 Free article.

6

Identical cells with different 3D genomes; cause and consequences?

Krijger PH, de Laat W. Krijger PH, et al. Among authors: de laat w. Curr Opin Genet Dev. 2013 Apr;23(2):191-6. doi: 10.1016/j.gde.2012.12.010. Epub 2013 Feb 14. Curr Opin Genet Dev. 2013. PMID: 23415810 Review.

7

Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells.

Holwerda SJ, van de Werken HJ, Ribeiro de Almeida C, Bergen IM, de Bruijn MJ, Verstegen MJ, Simonis M, Splinter E, Wijchers PJ, Hendriks RW, de Laat W. Holwerda SJ, et al. Among authors: de bruijn mj, de laat w. Nucleic Acids Res. 2013 Aug;41(14):6905-16. doi: 10.1093/nar/gkt491. Epub 2013 Jun 7. Nucleic Acids Res. 2013. PMID: 23748562 Free PMC article.

8

For genomes to stay in shape, insulators must be up to PAR.

Wijchers PJ, de Laat W. Wijchers PJ, et al. Among authors: de laat w. Cell. 2013 Sep 26;155(1):15-6. doi: 10.1016/j.cell.2013.09.012. Cell. 2013. PMID: 24074855 Free article.

9

Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA.

Léveillé N, Melo CA, Rooijers K, Díaz-Lagares A, Melo SA, Korkmaz G, Lopes R, Moqadam FA, Maia AR, Wijchers PJ, Geeven G, den Boer ML, Kalluri R, de Laat W, Esteller M, Agami R. Léveillé N, et al. Among authors: de laat w. Nat Commun. 2015 Mar 27;6:6520. doi: 10.1038/ncomms7520. Nat Commun. 2015. PMID: 25813522 Free PMC article.

10

Characterization and dynamics of pericentromere-associated domains in mice.

Wijchers PJ, Geeven G, Eyres M, Bergsma AJ, Janssen M, Verstegen M, Zhu Y, Schell Y, Vermeulen C, de Wit E, de Laat W. Wijchers PJ, et al. Among authors: de laat w, de wit e. Genome Res. 2015 Jul;25(7):958-69. doi: 10.1101/gr.186643.114. Epub 2015 Apr 16. Genome Res. 2015. PMID: 25883320 Free PMC article.

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