Wiemer EA - Search Results

1

Drug transporters and imatinib treatment: implications for clinical practice.

Eechoute K, Sparreboom A, Burger H, Franke RM, Schiavon G, Verweij J, Loos WJ, Wiemer EA, Mathijssen RH. Eechoute K, et al. Among authors: wiemer ea. Clin Cancer Res. 2011 Feb 1;17(3):406-15. doi: 10.1158/1078-0432.CCR-10-2250. Epub 2010 Dec 16. Clin Cancer Res. 2011. PMID: 21163869 Review.

2

RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: correlation with chemotherapeutic response.

Burger H, Foekens JA, Look MP, Meijer-van Gelder ME, Klijn JG, Wiemer EA, Stoter G, Nooter K. Burger H, et al. Among authors: wiemer ea. Clin Cancer Res. 2003 Feb;9(2):827-36. Clin Cancer Res. 2003. PMID: 12576456

3

Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump.

Burger H, van Tol H, Boersma AW, Brok M, Wiemer EA, Stoter G, Nooter K. Burger H, et al. Among authors: wiemer ea. Blood. 2004 Nov 1;104(9):2940-2. doi: 10.1182/blood-2004-04-1398. Epub 2004 Jul 13. Blood. 2004. PMID: 15251980 Free article.

4

Efflux kinetics and intracellular distribution of daunorubicin are not affected by major vault protein/lung resistance-related protein (vault) expression.

van Zon A, Mossink MH, Schoester M, Scheper RJ, Sonneveld P, Wiemer EA. van Zon A, et al. Among authors: wiemer ea. Cancer Res. 2004 Jul 15;64(14):4887-92. doi: 10.1158/0008-5472.CAN-03-3891. Cancer Res. 2004. PMID: 15256459

5

Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps.

Burger H, van Tol H, Brok M, Wiemer EA, de Bruijn EA, Guetens G, de Boeck G, Sparreboom A, Verweij J, Nooter K. Burger H, et al. Among authors: wiemer ea. Cancer Biol Ther. 2005 Jul;4(7):747-52. doi: 10.4161/cbt.4.7.1826. Epub 2005 Jul 9. Cancer Biol Ther. 2005. PMID: 15970668 Free article.

6

Activating mutations in c-KIT and PDGFRalpha are exclusively found in gastrointestinal stromal tumors and not in other tumors overexpressing these imatinib mesylate target genes.

Burger H, den Bakker MA, Kros JM, van Tol H, de Bruin AM, Oosterhuis W, van den Ingh HF, van der Harst E, de Schipper HP, Wiemer EA, Nooter K. Burger H, et al. Among authors: wiemer ea. Cancer Biol Ther. 2005 Nov;4(11):1270-4. doi: 10.4161/cbt.4.11.2253. Epub 2005 Nov 18. Cancer Biol Ther. 2005. PMID: 16294026 Free article.

7

Practical aspects of managing gastrointestinal stromal tumors.

Sleijfer S, Seynaeve C, Wiemer E, Verweij J. Sleijfer S, et al. Clin Colorectal Cancer. 2006 Nov;6 Suppl 1:S18-23. doi: 10.3816/ccc.2006.s.003. Clin Colorectal Cancer. 2006. PMID: 17101064 Review.

8

Improved insight into resistance mechanisms to imatinib in gastrointestinal stromal tumors: a basis for novel approaches and individualization of treatment.

Sleijfer S, Wiemer E, Seynaeve C, Verweij J. Sleijfer S, et al. Oncologist. 2007 Jun;12(6):719-26. doi: 10.1634/theoncologist.12-6-719. Oncologist. 2007. PMID: 17602061 Free article.

9

Pitfalls of the application of microdialysis in clinical oncology: controversial findings with docetaxel.

Loos WJ, Zamboni WC, Engels FK, de Bruijn P, Lam MH, de Wit R, Verweij J, Wiemer EA. Loos WJ, et al. Among authors: wiemer ea. J Pharm Biomed Anal. 2007 Oct 18;45(2):288-94. doi: 10.1016/j.jpba.2007.07.023. Epub 2007 Jul 26. J Pharm Biomed Anal. 2007. PMID: 17804188

10

Drug Insight: gastrointestinal stromal tumors (GIST)--the solid tumor model for cancer-specific treatment.

Sleijfer S, Wiemer E, Verweij J. Sleijfer S, et al. Nat Clin Pract Oncol. 2008 Feb;5(2):102-11. doi: 10.1038/ncponc1037. Nat Clin Pract Oncol. 2008. PMID: 18235442 Review.

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