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IL-27 promotes T cell-dependent colitis through multiple mechanisms.
Cox JH, Kljavin NM, Ramamoorthi N, Diehl L, Batten M, Ghilardi N. Cox JH, et al. Among authors: ghilardi n. J Exp Med. 2011 Jan 17;208(1):115-23. doi: 10.1084/jem.20100410. Epub 2010 Dec 20. J Exp Med. 2011. PMID: 21173106 Free PMC article.
The biology and therapeutic potential of interleukin 27.
Batten M, Ghilardi N. Batten M, et al. Among authors: ghilardi n. J Mol Med (Berl). 2007 Jul;85(7):661-72. doi: 10.1007/s00109-007-0164-7. Epub 2007 Feb 10. J Mol Med (Berl). 2007. PMID: 17294231 Review.
Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1.
Xi H, Katschke KJ Jr, Helmy KY, Wark PA, Kljavin N, Clark H, Eastham-Anderson J, Shek T, Roose-Girma M, Ghilardi N, van Lookeren Campagne M. Xi H, et al. Among authors: ghilardi n. J Exp Med. 2010 Jan 18;207(1):7-16. doi: 10.1084/jem.20091508. Epub 2009 Dec 28. J Exp Med. 2010. PMID: 20038601 Free PMC article.
IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells.
Batten M, Ramamoorthi N, Kljavin NM, Ma CS, Cox JH, Dengler HS, Danilenko DM, Caplazi P, Wong M, Fulcher DA, Cook MC, King C, Tangye SG, de Sauvage FJ, Ghilardi N. Batten M, et al. Among authors: ghilardi n. J Exp Med. 2010 Dec 20;207(13):2895-906. doi: 10.1084/jem.20100064. Epub 2010 Nov 22. J Exp Med. 2010. PMID: 21098093 Free PMC article.
IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice.
Vijayan D, Mohd Redzwan N, Avery DT, Wirasinha RC, Brink R, Walters G, Adelstein S, Kobayashi M, Gray P, Elliott M, Wong M, King C, Vinuesa CG, Ghilardi N, Ma CS, Tangye SG, Batten M. Vijayan D, et al. Among authors: ghilardi n. J Immunol. 2016 Oct 15;197(8):3008-3017. doi: 10.4049/jimmunol.1600652. Epub 2016 Sep 12. J Immunol. 2016. PMID: 27619997
71 results