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Cell proliferation in the absence of E2F1-3.
Wenzel PL, Chong JL, Sáenz-Robles MT, Ferrey A, Hagan JP, Gomez YM, Rajmohan R, Sharma N, Chen HZ, Pipas JM, Robinson ML, Leone G. Wenzel PL, et al. Among authors: leone g. Dev Biol. 2011 Mar 1;351(1):35-45. doi: 10.1016/j.ydbio.2010.12.025. Epub 2010 Dec 23. Dev Biol. 2011. PMID: 21185283 Free PMC article.
Rb is critical in a mammalian tissue stem cell population.
Wenzel PL, Wu L, de Bruin A, Chong JL, Chen WY, Dureska G, Sites E, Pan T, Sharma A, Huang K, Ridgway R, Mosaliganti K, Sharp R, Machiraju R, Saltz J, Yamamoto H, Cross JC, Robinson ML, Leone G. Wenzel PL, et al. Among authors: leone g. Genes Dev. 2007 Jan 1;21(1):85-97. doi: 10.1101/gad.1485307. Genes Dev. 2007. PMID: 17210791 Free PMC article.
E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
Chong JL, Wenzel PL, Sáenz-Robles MT, Nair V, Ferrey A, Hagan JP, Gomez YM, Sharma N, Chen HZ, Ouseph M, Wang SH, Trikha P, Culp B, Mezache L, Winton DJ, Sansom OJ, Chen D, Bremner R, Cantalupo PG, Robinson ML, Pipas JM, Leone G. Chong JL, et al. Among authors: leone g. Nature. 2009 Dec 17;462(7275):930-4. doi: 10.1038/nature08677. Nature. 2009. PMID: 20016602 Free PMC article.
Atypical E2F repressors and activators coordinate placental development.
Ouseph MM, Li J, Chen HZ, Pécot T, Wenzel P, Thompson JC, Comstock G, Chokshi V, Byrne M, Forde B, Chong JL, Huang K, Machiraju R, de Bruin A, Leone G. Ouseph MM, et al. Among authors: leone g. Dev Cell. 2012 Apr 17;22(4):849-62. doi: 10.1016/j.devcel.2012.01.013. Dev Cell. 2012. PMID: 22516201 Free PMC article.
Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.
Liu H, Tang X, Srivastava A, Pécot T, Daniel P, Hemmelgarn B, Reyes S, Fackler N, Bajwa A, Kladney R, Koivisto C, Chen Z, Wang Q, Huang K, Machiraju R, Sáenz-Robles MT, Cantalupo P, Pipas JM, Leone G. Liu H, et al. Among authors: leone g. Nat Cell Biol. 2015 Aug;17(8):1036-48. doi: 10.1038/ncb3210. Epub 2015 Jul 20. Nat Cell Biol. 2015. PMID: 26192440 Free PMC article.
1,352 results