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101 results

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A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions.
Fleming SM, Mulligan CK, Richter F, Mortazavi F, Lemesre V, Frias C, Zhu C, Stewart A, Gozes I, Morimoto B, Chesselet MF. Fleming SM, et al. Among authors: mortazavi f. Mol Cell Neurosci. 2011 Mar;46(3):597-606. doi: 10.1016/j.mcn.2010.12.011. Epub 2010 Dec 27. Mol Cell Neurosci. 2011. PMID: 21193046 Free PMC article.
Strengths and limitations of genetic mouse models of Parkinson's disease.
Chesselet MF, Fleming S, Mortazavi F, Meurers B. Chesselet MF, et al. Among authors: mortazavi f. Parkinsonism Relat Disord. 2008;14 Suppl 2(Suppl 2):S84-7. doi: 10.1016/j.parkreldis.2008.04.004. Epub 2008 Jun 27. Parkinsonism Relat Disord. 2008. PMID: 18585084 Free PMC article. Review.
Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein.
Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Lu XH, et al. Among authors: mortazavi f. J Neurosci. 2009 Feb 18;29(7):1962-76. doi: 10.1523/JNEUROSCI.5351-08.2009. J Neurosci. 2009. PMID: 19228951 Free PMC article.
A GCase chaperone improves motor function in a mouse model of synucleinopathy.
Richter F, Fleming SM, Watson M, Lemesre V, Pellegrino L, Ranes B, Zhu C, Mortazavi F, Mulligan CK, Sioshansi PC, Hean S, De La Rosa K, Khanna R, Flanagan J, Lockhart DJ, Wustman BA, Clark SW, Chesselet MF. Richter F, et al. Among authors: mortazavi f. Neurotherapeutics. 2014 Oct;11(4):840-56. doi: 10.1007/s13311-014-0294-x. Neurotherapeutics. 2014. PMID: 25037721 Free PMC article.
Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome.
Chou AP, Maidment N, Klintenberg R, Casida JE, Li S, Fitzmaurice AG, Fernagut PO, Mortazavi F, Chesselet MF, Bronstein JM. Chou AP, et al. Among authors: mortazavi f. J Biol Chem. 2008 Dec 12;283(50):34696-703. doi: 10.1074/jbc.M802210200. Epub 2008 Sep 25. J Biol Chem. 2008. PMID: 18818210 Free PMC article.
Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice.
Richter F, Gabby L, McDowell KA, Mulligan CK, De La Rosa K, Sioshansi PC, Mortazavi F, Cely I, Ackerson LC, Tsan L, Murphy NP, Maidment NT, Chesselet MF. Richter F, et al. Among authors: mortazavi f. Neurobiol Aging. 2017 Mar;51:54-66. doi: 10.1016/j.neurobiolaging.2016.11.015. Epub 2016 Dec 1. Neurobiol Aging. 2017. PMID: 28038352 Free PMC article.
A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins.
Ruan QT, Yazdani N, Blum BC, Beierle JA, Lin W, Coelho MA, Fultz EK, Healy AF, Shahin JR, Kandola AK, Luttik KP, Zheng K, Smith NJ, Cheung J, Mortazavi F, Apicco DJ, Ragu Varman D, Ramamoorthy S, Ash PEA, Rosene DL, Emili A, Wolozin B, Szumlinski KK, Bryant CD. Ruan QT, et al. Among authors: mortazavi f. J Neurosci. 2020 Jan 2;40(1):107-130. doi: 10.1523/JNEUROSCI.1808-19.2019. Epub 2019 Nov 8. J Neurosci. 2020. PMID: 31704785 Free PMC article.
101 results