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Page 1
A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions.
Fleming SM, Mulligan CK, Richter F, Mortazavi F, Lemesre V, Frias C, Zhu C, Stewart A, Gozes I, Morimoto B, Chesselet MF. Fleming SM, et al. Among authors: mulligan ck. Mol Cell Neurosci. 2011 Mar;46(3):597-606. doi: 10.1016/j.mcn.2010.12.011. Epub 2010 Dec 27. Mol Cell Neurosci. 2011. PMID: 21193046 Free PMC article.
Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons.
Richter F, Gao F, Medvedeva V, Lee P, Bove N, Fleming SM, Michaud M, Lemesre V, Patassini S, De La Rosa K, Mulligan CK, Sioshansi PC, Zhu C, Coppola G, Bordet T, Pruss RM, Chesselet MF. Richter F, et al. Among authors: mulligan ck. Neurobiol Dis. 2014 Sep;69:263-75. doi: 10.1016/j.nbd.2014.05.012. Epub 2014 May 18. Neurobiol Dis. 2014. PMID: 24844147 Free PMC article.
A GCase chaperone improves motor function in a mouse model of synucleinopathy.
Richter F, Fleming SM, Watson M, Lemesre V, Pellegrino L, Ranes B, Zhu C, Mortazavi F, Mulligan CK, Sioshansi PC, Hean S, De La Rosa K, Khanna R, Flanagan J, Lockhart DJ, Wustman BA, Clark SW, Chesselet MF. Richter F, et al. Among authors: mulligan ck. Neurotherapeutics. 2014 Oct;11(4):840-56. doi: 10.1007/s13311-014-0294-x. Neurotherapeutics. 2014. PMID: 25037721 Free PMC article.
Alpha-synuclein pathology, microgliosis, and parvalbumin neuron loss in the amygdala associated with enhanced fear in the Thy1-aSyn model of Parkinson's disease.
Torres ERS, Stanojlovic M, Zelikowsky M, Bonsberger J, Hean S, Mulligan C, Baldauf L, Fleming S, Masliah E, Chesselet MF, Fanselow MS, Richter F. Torres ERS, et al. Neurobiol Dis. 2021 Oct;158:105478. doi: 10.1016/j.nbd.2021.105478. Epub 2021 Aug 11. Neurobiol Dis. 2021. PMID: 34390837 Free PMC article.
Impaired baroreflex function in mice overexpressing alpha-synuclein.
Fleming SM, Jordan MC, Mulligan CK, Masliah E, Holden JG, Millard RW, Chesselet MF, Roos KP. Fleming SM, et al. Among authors: mulligan ck. Front Neurol. 2013 Jul 23;4:103. doi: 10.3389/fneur.2013.00103. eCollection 2013. Front Neurol. 2013. PMID: 23888153 Free PMC article.
Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice.
Richter F, Gabby L, McDowell KA, Mulligan CK, De La Rosa K, Sioshansi PC, Mortazavi F, Cely I, Ackerson LC, Tsan L, Murphy NP, Maidment NT, Chesselet MF. Richter F, et al. Among authors: mulligan ck. Neurobiol Aging. 2017 Mar;51:54-66. doi: 10.1016/j.neurobiolaging.2016.11.015. Epub 2016 Dec 1. Neurobiol Aging. 2017. PMID: 28038352 Free PMC article.