Kawaguchi T - Search Results

1

Association of SLCO1B3 polymorphism with intracellular accumulation of imatinib in leukocytes in patients with chronic myeloid leukemia.

Nambu T, Hamada A, Nakashima R, Yuki M, Kawaguchi T, Mitsuya H, Saito H. Nambu T, et al. Among authors: kawaguchi t. Biol Pharm Bull. 2011;34(1):114-9. doi: 10.1248/bpb.34.114. Biol Pharm Bull. 2011. PMID: 21212528 Free PMC article.

2

Relationship between an effective dose of imatinib, body surface area, and trough drug levels in patients with chronic myeloid leukemia.

Kawaguchi T, Hamada A, Hirayama C, Nakashima R, Nambu T, Yamakawa Y, Watanabe H, Horikawa K, Mitsuya H, Saito H. Kawaguchi T, et al. Int J Hematol. 2009 Jun;89(5):642-8. doi: 10.1007/s12185-009-0315-4. Epub 2009 Apr 25. Int J Hematol. 2009. PMID: 19396513 Free article. Clinical Trial.

3

Contribution of BCR-ABL-independent activation of ERK1/2 to acquired imatinib resistance in K562 chronic myeloid leukemia cells.

Nambu T, Araki N, Nakagawa A, Kuniyasu A, Kawaguchi T, Hamada A, Saito H. Nambu T, et al. Among authors: kawaguchi t. Cancer Sci. 2010 Jan;101(1):137-42. doi: 10.1111/j.1349-7006.2009.01365.x. Epub 2009 Sep 14. Cancer Sci. 2010. PMID: 19843070 Free PMC article.

4

Association of genetic polymorphisms in the influx transporter SLCO1B3 and the efflux transporter ABCB1 with imatinib pharmacokinetics in patients with chronic myeloid leukemia.

Yamakawa Y, Hamada A, Nakashima R, Yuki M, Hirayama C, Kawaguchi T, Saito H. Yamakawa Y, et al. Among authors: kawaguchi t. Ther Drug Monit. 2011 Apr;33(2):244-50. doi: 10.1097/FTD.0b013e31820beb02. Ther Drug Monit. 2011. PMID: 21311410

5

High-performance liquid chromatographic assay for the determination of nilotinib in human plasma.

Yuki M, Yamakawa Y, Uchida T, Nambu T, Kawaguchi T, Hamada A, Saito H. Yuki M, et al. Among authors: kawaguchi t. Biol Pharm Bull. 2011;34(7):1126-8. doi: 10.1248/bpb.34.1126. Biol Pharm Bull. 2011. PMID: 21720025 Free article.

6

Distinct interaction of nilotinib and imatinib with P-Glycoprotein in intracellular accumulation and cytotoxicity in CML Cell Line K562 cells.

Yamakawa Y, Hamada A, Uchida T, Sato D, Yuki M, Hayashi M, Kawaguchi T, Saito H. Yamakawa Y, et al. Among authors: kawaguchi t. Biol Pharm Bull. 2014;37(8):1330-5. doi: 10.1248/bpb.b14-00254. Biol Pharm Bull. 2014. PMID: 25087954 Free article.

7

Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells.

Hirayama C, Watanabe H, Nakashima R, Nanbu T, Hamada A, Kuniyasu A, Nakayama H, Kawaguchi T, Saito H. Hirayama C, et al. Among authors: kawaguchi t. Pharm Res. 2008 Apr;25(4):827-35. doi: 10.1007/s11095-007-9376-3. Epub 2007 Oct 13. Pharm Res. 2008. PMID: 17934801

8

Pharmacokinetic impact of SLCO1A2 polymorphisms on imatinib disposition in patients with chronic myeloid leukemia.

Yamakawa Y, Hamada A, Shuto T, Yuki M, Uchida T, Kai H, Kawaguchi T, Saito H. Yamakawa Y, et al. Among authors: kawaguchi t. Clin Pharmacol Ther. 2011 Jul;90(1):157-63. doi: 10.1038/clpt.2011.102. Epub 2011 Jun 1. Clin Pharmacol Ther. 2011. PMID: 21633340 Free article.

9

Inhibition of 5'-deoxy-5-fluorouridine phosphorolysis by acyclopyrimidinenucleosides in intestinal tissue homogenates.

Hamada A, Fukushima S, Saneyoshi M, Kawaguchi T, Nakano M. Hamada A, et al. Among authors: kawaguchi t. Biol Pharm Bull. 1995 Jan;18(1):172-5. doi: 10.1248/bpb.18.172. Biol Pharm Bull. 1995. PMID: 7735236 Free article.

10

Acyclothymidine alleviates intestinal toxicity of 5'-deoxy-5-fluorouridine without loss of antitumor activity in mice.

Hamada A, Fukushima S, Saneyoshi M, Shimizu S, Kawaguchi T, Nakano M. Hamada A, et al. Among authors: kawaguchi t. Biol Pharm Bull. 1996 Oct;19(10):1362-6. doi: 10.1248/bpb.19.1362. Biol Pharm Bull. 1996. PMID: 8913513 Free article.

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