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Interleukin-4-inducing principle from Schistosoma mansoni eggs contains a functional C-terminal nuclear localization signal necessary for nuclear translocation in mammalian cells but not for its uptake.
Kaur I, Schramm G, Everts B, Scholzen T, Kindle KB, Beetz C, Montiel-Duarte C, Blindow S, Jones AT, Haas H, Stolnik S, Heery DM, Falcone FH. Kaur I, et al. Among authors: blindow s. Infect Immun. 2011 Apr;79(4):1779-88. doi: 10.1128/IAI.01048-10. Epub 2011 Jan 10. Infect Immun. 2011. PMID: 21220486 Free PMC article.
A Crystallin Fold in the Interleukin-4-inducing Principle of Schistosoma mansoni Eggs (IPSE/α-1) Mediates IgE Binding for Antigen-independent Basophil Activation.
Meyer NH, Mayerhofer H, Tripsianes K, Blindow S, Barths D, Mewes A, Weimar T, Köhli T, Bade S, Madl T, Frey A, Haas H, Mueller-Dieckmann J, Sattler M, Schramm G. Meyer NH, et al. Among authors: blindow s. J Biol Chem. 2015 Sep 4;290(36):22111-26. doi: 10.1074/jbc.M115.675066. Epub 2015 Jul 10. J Biol Chem. 2015. PMID: 26163514 Free PMC article.