Seabra L - Search Results

1

Therapeutic targeting the loss of the birt-hogg-dube suppressor gene.

Lu X, Wei W, Fenton J, Nahorski MS, Rabai E, Reiman A, Seabra L, Nagy Z, Latif F, Maher ER. Lu X, et al. Among authors: seabra l. Mol Cancer Ther. 2011 Jan;10(1):80-9. doi: 10.1158/1535-7163.MCT-10-0628. Mol Cancer Ther. 2011. PMID: 21220493

2

Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN).

Lu X, Boora U, Seabra L, Rabai EM, Fenton J, Reiman A, Nagy Z, Maher ER. Lu X, et al. Among authors: seabra l. Oncogene. 2014 Feb 20;33(8):956-65. doi: 10.1038/onc.2013.27. Epub 2013 Feb 18. Oncogene. 2014. PMID: 23416984

3

Birt Hogg-Dubé syndrome-associated FLCN mutations disrupt protein stability.

Nahorski MS, Reiman A, Lim DH, Nookala RK, Seabra L, Lu X, Fenton J, Boora U, Nordenskjöld M, Latif F, Hurst LD, Maher ER. Nahorski MS, et al. Among authors: seabra l. Hum Mutat. 2011 Aug;32(8):921-9. doi: 10.1002/humu.21519. Epub 2011 Jul 12. Hum Mutat. 2011. PMID: 21538689

4

Gene expression and protein array studies of folliculin-regulated pathways.

Reiman A, Lu X, Seabra L, Boora U, Nahorski MS, Wei W, Maher ER. Reiman A, et al. Among authors: seabra l. Anticancer Res. 2012 Nov;32(11):4663-70. Anticancer Res. 2012. PMID: 23155228

5

Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis.

Nahorski MS, Seabra L, Straatman-Iwanowska A, Wingenfeld A, Reiman A, Lu X, Klomp JA, Teh BT, Hatzfeld M, Gissen P, Maher ER. Nahorski MS, et al. Among authors: seabra l. Hum Mol Genet. 2012 Dec 15;21(24):5268-79. doi: 10.1093/hmg/dds378. Epub 2012 Sep 10. Hum Mol Genet. 2012. PMID: 22965878 Free PMC article.

6

Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4.

Warenius HM, Kilburn JD, Essex JW, Maurer RI, Blaydes JP, Agarwala U, Seabra LA. Warenius HM, et al. Mol Cancer. 2011 Jun 13;10:72. doi: 10.1186/1476-4598-10-72. Mol Cancer. 2011. PMID: 21668989 Free PMC article.

7

Late G1 accumulation after 2 Gy of gamma-irradiation is related to endogenous Raf-1 protein expression and intrinsic radiosensitivity in human cells.

Warenius HM, Jones M, Jones MD, Browning PG, Seabra LA, Thompson CC. Warenius HM, et al. Among authors: seabra la. Br J Cancer. 1998 Apr;77(8):1220-8. doi: 10.1038/bjc.1998.206. Br J Cancer. 1998. PMID: 9579826 Free PMC article.

8

Proteomic co-expression of cyclin-dependent kinases 1 and 4 in human cancer cells.

Seabra L, Warenius H. Seabra L, et al. Eur J Cancer. 2007 Jun;43(9):1483-92. doi: 10.1016/j.ejca.2007.03.014. Epub 2007 May 3. Eur J Cancer. 2007. PMID: 17481885

9

Theranostic proteomic profiling of cyclins, cyclin dependent kinases and Ras in human cancer cell lines is dependent on p53 mutational status.

Warenius HM, Seabra L, Kyritsi L, White R, Dormer R, Anandappa S, Thomas C, Howarth A. Warenius HM, et al. Among authors: seabra l. Int J Oncol. 2008 Apr;32(4):895-907. Int J Oncol. 2008. PMID: 18360717

10

Dynamic heterogeneity of proteomic expression in human cancer cells does not affect Cdk1/Cdk4 co-expression.

Warenius H, Howarth A, Seabra L, Kyritsi L, Dormer R, Anandappa S, Thomas C. Warenius H, et al. Among authors: seabra l. J Exp Ther Oncol. 2008;7(3):237-54. J Exp Ther Oncol. 2008. PMID: 19066132

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