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VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration.
Razorenova OV, Finger EC, Colavitti R, Chernikova SB, Boiko AD, Chan CK, Krieg A, Bedogni B, LaGory E, Weissman IL, Broome-Powell M, Giaccia AJ. Razorenova OV, et al. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1931-6. doi: 10.1073/pnas.1011777108. Epub 2011 Jan 13. Proc Natl Acad Sci U S A. 2011. PMID: 21233420 Free PMC article.
The apoptosis repressor with a CARD domain (ARC) gene is a direct hypoxia-inducible factor 1 target gene and promotes survival and proliferation of VHL-deficient renal cancer cells.
Razorenova OV, Castellini L, Colavitti R, Edgington LE, Nicolau M, Huang X, Bedogni B, Mills EM, Bogyo M, Giaccia AJ. Razorenova OV, et al. Mol Cell Biol. 2014 Feb;34(4):739-51. doi: 10.1128/MCB.00644-12. Epub 2013 Dec 16. Mol Cell Biol. 2014. PMID: 24344197 Free PMC article.
Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability.
Chernikova SB, Razorenova OV, Higgins JP, Sishc BJ, Nicolau M, Dorth JA, Chernikova DA, Kwok S, Brooks JD, Bailey SM, Game JC, Brown JM. Chernikova SB, et al. Among authors: razorenova ov. Cancer Res. 2012 Apr 15;72(8):2111-9. doi: 10.1158/0008-5472.CAN-11-2209. Epub 2012 Feb 21. Cancer Res. 2012. PMID: 22354749 Free PMC article.
37 results