Nathwani AC - Search Results

1

Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins.

Nathwani AC, Rosales C, McIntosh J, Rastegarlari G, Nathwani D, Raj D, Nawathe S, Waddington SN, Bronson R, Jackson S, Donahue RE, High KA, Mingozzi F, Ng CY, Zhou J, Spence Y, McCarville MB, Valentine M, Allay J, Coleman J, Sleep S, Gray JT, Nienhuis AW, Davidoff AM. Nathwani AC, et al. Among authors: nathwani d. Mol Ther. 2011 May;19(5):876-85. doi: 10.1038/mt.2010.274. Epub 2011 Jan 18. Mol Ther. 2011. PMID: 21245849 Free PMC article.

2

Adenovirus-mediated expresssion of the murine ecotropic receptor facilitates transduction of human hematopoietic cells with an ecotropic retroviral vector.

Nathwani AC, Persons DA, Stevenson SC, Frare P, McClelland A, Nienhuis AW, Vanin EF. Nathwani AC, et al. Gene Ther. 1999 Aug;6(8):1456-68. doi: 10.1038/sj.gt.3300974. Gene Ther. 1999. PMID: 10467370

3

Efficient gene transfer into human cord blood CD34+ cells and the CD34+CD38- subset using highly purified recombinant adeno-associated viral vector preparations that are free of helper virus and wild-type AAV.

Nathwani AC, Hanawa H, Vandergriff J, Kelly P, Vanin EF, Nienhuis AW. Nathwani AC, et al. Gene Ther. 2000 Feb;7(3):183-95. doi: 10.1038/sj.gt.3301068. Gene Ther. 2000. PMID: 10694794

4

Highly efficient gene transfer into cord blood nonobese diabetic/severe combined immunodeficiency repopulating cells by oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein.

Kelly PF, Vandergriff J, Nathwani A, Nienhuis AW, Vanin EF. Kelly PF, et al. Blood. 2000 Aug 15;96(4):1206-14. Blood. 2000. PMID: 10942359 Free article.

5

Factors influencing in vivo transduction by recombinant adeno-associated viral vectors expressing the human factor IX cDNA.

Nathwani AC, Davidoff A, Hanawa H, Zhou JF, Vanin EF, Nienhuis AW. Nathwani AC, et al. Blood. 2001 Mar 1;97(5):1258-65. doi: 10.1182/blood.v97.5.1258. Blood. 2001. PMID: 11222368 Free article.

6

Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human blood.

Hanawa H, Kelly PF, Nathwani AC, Persons DA, Vandergriff JA, Hargrove P, Vanin EF, Nienhuis AW. Hanawa H, et al. Among authors: nathwani ac. Mol Ther. 2002 Mar;5(3):242-51. doi: 10.1006/mthe.2002.0549. Mol Ther. 2002. PMID: 11863413 Free article.

7

rAAV-mediated long-term liver-generated expression of an angiogenesis inhibitor can restrict renal tumor growth in mice.

Davidoff AM, Nathwani AC, Spurbeck WW, Ng CY, Zhou J, Vanin EF. Davidoff AM, et al. Among authors: nathwani ac. Cancer Res. 2002 Jun 1;62(11):3077-83. Cancer Res. 2002. PMID: 12036917

8

Sustained high-level expression of human factor IX (hFIX) after liver-targeted delivery of recombinant adeno-associated virus encoding the hFIX gene in rhesus macaques.

Nathwani AC, Davidoff AM, Hanawa H, Hu Y, Hoffer FA, Nikanorov A, Slaughter C, Ng CY, Zhou J, Lozier JN, Mandrell TD, Vanin EF, Nienhuis AW. Nathwani AC, et al. Blood. 2002 Sep 1;100(5):1662-9. doi: 10.1182/blood-2002-02-0589. Blood. 2002. PMID: 12176886 Free article.

9

Sex significantly influences transduction of murine liver by recombinant adeno-associated viral vectors through an androgen-dependent pathway.

Davidoff AM, Ng CY, Zhou J, Spence Y, Nathwani AC. Davidoff AM, et al. Among authors: nathwani ac. Blood. 2003 Jul 15;102(2):480-8. doi: 10.1182/blood-2002-09-2889. Epub 2003 Mar 13. Blood. 2003. PMID: 12637328 Free article.

10

Current status of gene therapy for hemophilia.

Nathwani AC, Nienhuis AW, Davidoff AM. Nathwani AC, et al. Curr Hematol Rep. 2003 Jul;2(4):319-27. Curr Hematol Rep. 2003. PMID: 12901329 Review.

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