Hachiya A - Search Results

1

K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism.

Hachiya A, Kodama EN, Schuckmann MM, Kirby KA, Michailidis E, Sakagami Y, Oka S, Singh K, Sarafianos SG. Hachiya A, et al. PLoS One. 2011 Jan 13;6(1):e16242. doi: 10.1371/journal.pone.0016242. PLoS One. 2011. PMID: 21249155 Free PMC article.

2

[Evaluation of an anti-HIV-1/2 antibodies detection kit based on counting immunoassay].

Hachiya A, Oka S. Hachiya A, et al. Kansenshogaku Zasshi. 2001 Feb;75(2):103-9. doi: 10.11150/kansenshogakuzasshi1970.75.103. Kansenshogaku Zasshi. 2001. PMID: 11260875 Japanese.

3

Augmentation of human immunodeficiency virus type 1 subtype E (CRF01_AE) multiple-drug resistance by insertion of a foreign 11-amino-acid fragment into the reverse transcriptase.

Sato H, Tomita Y, Ebisawa K, Hachiya A, Shibamura K, Shiino T, Yang R, Tatsumi M, Gushi K, Umeyama H, Oka S, Takebe Y, Nagai Y. Sato H, et al. Among authors: hachiya a. J Virol. 2001 Jun;75(12):5604-13. doi: 10.1128/JVI.75.12.5604-5613.2001. J Virol. 2001. PMID: 11356968 Free PMC article.

4

Isolation and molecular characterization of a nelfinavir (NFV)-resistant human immunodeficiency virus type 1 that exhibits NFV-dependent enhancement of replication.

Matsuoka-Aizawa S, Sato H, Hachiya A, Tsuchiya K, Takebe Y, Gatanaga H, Kimura S, Oka S. Matsuoka-Aizawa S, et al. Among authors: hachiya a. J Virol. 2003 Jan;77(1):318-27. doi: 10.1128/jvi.77.1.318-327.2003. J Virol. 2003. PMID: 12477837 Free PMC article.

5

"All-in-One Assay", a direct phenotypic anti-human immunodeficiency virus type 1 drug resistance assay for three-drug combination therapies that takes into consideration in vivo drug concentrations.

Hachiya A, Matsuoka-Aizawa S, Tsuchiya K, Gatanaga H, Kimura S, Tatsumi M, Oka S. Hachiya A, et al. J Virol Methods. 2003 Jul;111(1):43-53. doi: 10.1016/s0166-0934(03)00150-2. J Virol Methods. 2003. PMID: 12821196

6

Novel patterns of nevirapine resistance-associated mutations of human immunodeficiency virus type 1 in treatment-naïve patients.

Hachiya A, Gatanaga H, Kodama E, Ikeuchi M, Matsuoka M, Harada S, Mitsuya H, Kimura S, Oka S. Hachiya A, et al. Virology. 2004 Oct 1;327(2):215-24. doi: 10.1016/j.virol.2004.07.001. Virology. 2004. PMID: 15351209 Free article.

7

Mutations other than 103N in human immunodeficiency virus type 1 reverse transcriptase (RT) emerge from K103R polymorphism under non-nucleoside RT inhibitor pressure.

Gatanaga H, Hachiya A, Kimura S, Oka S. Gatanaga H, et al. Among authors: hachiya a. Virology. 2006 Jan 20;344(2):354-62. doi: 10.1016/j.virol.2005.09.005. Epub 2005 Oct 10. Virology. 2006. PMID: 16219331 Free article.

8

Amino acid mutation N348I in the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase confers multiclass resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors.

Hachiya A, Kodama EN, Sarafianos SG, Schuckmann MM, Sakagami Y, Matsuoka M, Takiguchi M, Gatanaga H, Oka S. Hachiya A, et al. J Virol. 2008 Apr;82(7):3261-70. doi: 10.1128/JVI.01154-07. Epub 2008 Jan 23. J Virol. 2008. PMID: 18216099 Free PMC article.

9

Clinical relevance of substitutions in the connection subdomain and RNase H domain of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naïve patients.

Hachiya A, Shimane K, Sarafianos SG, Kodama EN, Sakagami Y, Negishi F, Koizumi H, Gatanaga H, Matsuoka M, Takiguchi M, Oka S. Hachiya A, et al. Antiviral Res. 2009 Jun;82(3):115-21. doi: 10.1016/j.antiviral.2009.02.189. Epub 2009 Feb 21. Antiviral Res. 2009. PMID: 19428602 Free PMC article.

10

Combination of V106I and V179D polymorphic mutations in human immunodeficiency virus type 1 reverse transcriptase confers resistance to efavirenz and nevirapine but not etravirine.

Gatanaga H, Ode H, Hachiya A, Hayashida T, Sato H, Oka S. Gatanaga H, et al. Among authors: hachiya a. Antimicrob Agents Chemother. 2010 Apr;54(4):1596-602. doi: 10.1128/AAC.01480-09. Epub 2010 Feb 1. Antimicrob Agents Chemother. 2010. PMID: 20124001 Free PMC article.

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