Liu Y - Search Results

1

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.

Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim SH, Ito S, Yang C, Wang P, Xiao MT, Liu LX, Jiang WQ, Liu J, Zhang JY, Wang B, Frye S, Zhang Y, Xu YH, Lei QY, Guan KL, Zhao SM, Xiong Y. Xu W, et al. Among authors: liu j, liu y, liu lx. Cancer Cell. 2011 Jan 18;19(1):17-30. doi: 10.1016/j.ccr.2010.12.014. Cancer Cell. 2011. PMID: 21251613 Free PMC article.

2

Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors.

Xiao M, Yang H, Xu W, Ma S, Lin H, Zhu H, Liu L, Liu Y, Yang C, Xu Y, Zhao S, Ye D, Xiong Y, Guan KL. Xiao M, et al. Among authors: liu y, liu l. Genes Dev. 2012 Jun 15;26(12):1326-38. doi: 10.1101/gad.191056.112. Epub 2012 Jun 7. Genes Dev. 2012. PMID: 22677546 Free PMC article.

3

Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer.

Zhao D, Zou SW, Liu Y, Zhou X, Mo Y, Wang P, Xu YH, Dong B, Xiong Y, Lei QY, Guan KL. Zhao D, et al. Among authors: liu y. Cancer Cell. 2013 Apr 15;23(4):464-76. doi: 10.1016/j.ccr.2013.02.005. Epub 2013 Mar 21. Cancer Cell. 2013. PMID: 23523103 Free PMC article.

4

IDH1 mutations inhibit multiple α-ketoglutarate-dependent dioxygenase activities in astroglioma.

Liu Y, Jiang W, Liu J, Zhao S, Xiong J, Mao Y, Wang Y. Liu Y, et al. Among authors: liu j. J Neurooncol. 2012 Sep;109(2):253-60. doi: 10.1007/s11060-012-0914-4. Epub 2012 Jul 8. J Neurooncol. 2012. PMID: 22772731

5

Rapid diagnosis of IDH1-mutated gliomas by 2-HG detection with gas chromatography mass spectrometry.

Xu H, Xia YK, Li CJ, Zhang JY, Liu Y, Yi W, Qin ZY, Chen L, Shi ZF, Quan K, Yang ZX, Guan KL, Xiong Y, Ng HK, Ye D, Hua W, Mao Y. Xu H, et al. Among authors: liu y. Lab Invest. 2019 Apr;99(4):588-598. doi: 10.1038/s41374-018-0163-z. Epub 2018 Dec 20. Lab Invest. 2019. PMID: 30573870 Free article.

6

Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses.

Chen LL, Morcelle C, Cheng ZL, Chen X, Xu Y, Gao Y, Song J, Li Z, Smith MD, Shi M, Zhu Y, Zhou N, Cheng M, He C, Liu KY, Lu G, Zhang L, Zhang C, Zhang J, Sun Y, Qi T, Lyu Y, Ren ZZ, Tan XM, Yin J, Lan F, Liu Y, Yang H, Qian M, Duan C, Chang X, Zhou Y, Shen L, Baldwin AS, Guan KL, Xiong Y, Ye D. Chen LL, et al. Among authors: liu y, liu ky. Nat Cell Biol. 2022 Mar;24(3):353-363. doi: 10.1038/s41556-022-00853-8. Epub 2022 Mar 7. Nat Cell Biol. 2022. PMID: 35256775 Free PMC article.

7

Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.

Lv L, Li D, Zhao D, Lin R, Chu Y, Zhang H, Zha Z, Liu Y, Li Z, Xu Y, Wang G, Huang Y, Xiong Y, Guan KL, Lei QY. Lv L, et al. Among authors: liu y. Mol Cell. 2011 Jun 24;42(6):719-30. doi: 10.1016/j.molcel.2011.04.025. Mol Cell. 2011. PMID: 21700219 Free PMC article.

8

BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma.

Li JT, Yin M, Wang D, Wang J, Lei MZ, Zhang Y, Liu Y, Zhang L, Zou SW, Hu LP, Zhang ZG, Wang YP, Wen WY, Lu HJ, Chen ZJ, Su D, Lei QY. Li JT, et al. Among authors: liu y. Nat Cell Biol. 2020 Feb;22(2):167-174. doi: 10.1038/s41556-019-0455-6. Epub 2020 Feb 6. Nat Cell Biol. 2020. PMID: 32029896

9

ALDH1A1 Activity in Tumor-Initiating Cells Remodels Myeloid-Derived Suppressor Cells to Promote Breast Cancer Progression.

Liu C, Qiang J, Deng Q, Xia J, Deng L, Zhou L, Wang D, He X, Liu Y, Zhao B, Lv J, Yu Z, Lei QY, Shao ZM, Zhang XY, Zhang L, Liu S. Liu C, et al. Among authors: liu y, liu s. Cancer Res. 2021 Dec 1;81(23):5919-5934. doi: 10.1158/0008-5472.CAN-21-1337. Epub 2021 Sep 27. Cancer Res. 2021. PMID: 34580061

10

Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis.

Sun R, Zhang Z, Bao R, Guo X, Gu Y, Yang W, Wei J, Chen X, Tong L, Meng J, Zhong C, Zhang C, Zhang J, Sun Y, Ling C, Tong X, Yu FX, Yu H, Qu W, Zhao B, Guo W, Qian M, Saiyin H, Liu Y, Liu RH, Xie C, Liu W, Xiong Y, Guan KL, Shi Y, Wang P, Ye D. Sun R, et al. Among authors: liu y, liu rh, liu w. J Hepatol. 2022 Aug;77(2):453-466. doi: 10.1016/j.jhep.2022.02.030. Epub 2022 Mar 12. J Hepatol. 2022. PMID: 35292350

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