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Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.
Xu W, Yang H, Liu Y, Yang Y, Wang P, Kim SH, Ito S, Yang C, Wang P, Xiao MT, Liu LX, Jiang WQ, Liu J, Zhang JY, Wang B, Frye S, Zhang Y, Xu YH, Lei QY, Guan KL, Zhao SM, Xiong Y. Xu W, et al. Among authors: yang c, yang h, yang y. Cancer Cell. 2011 Jan 18;19(1):17-30. doi: 10.1016/j.ccr.2010.12.014. Cancer Cell. 2011. PMID: 21251613 Free PMC article.
Crystallization and preliminary crystallographic analysis of nosiheptide-resistance methyltransferase from Streptomyces actuosus in complex with SAM.
Yang H, Wang P, Dong Z, Li X, Gong R, Yang Y, Li Z, Xu Y, Xu Y. Yang H, et al. Among authors: yang y. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 May 1;66(Pt 5):579-82. doi: 10.1107/S1744309110011395. Epub 2010 Apr 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20445264 Free PMC article.
Par complex cluster formation mediated by phase separation.
Liu Z, Yang Y, Gu A, Xu J, Mao Y, Lu H, Hu W, Lei QY, Li Z, Zhang M, Cai Y, Wen W. Liu Z, et al. Among authors: yang y. Nat Commun. 2020 May 8;11(1):2266. doi: 10.1038/s41467-020-16135-6. Nat Commun. 2020. PMID: 32385244 Free PMC article.
LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation.
Fang R, Chen F, Dong Z, Hu D, Barbera AJ, Clark EA, Fang J, Yang Y, Mei P, Rutenberg M, Li Z, Zhang Y, Xu Y, Yang H, Wang P, Simon MD, Zhou Q, Li J, Marynick MP, Li X, Lu H, Kaiser UB, Kingston RE, Xu Y, Shi YG. Fang R, et al. Among authors: yang h, yang y. Mol Cell. 2013 Feb 7;49(3):558-70. doi: 10.1016/j.molcel.2012.11.019. Epub 2012 Dec 20. Mol Cell. 2013. PMID: 23260659 Free PMC article.
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