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Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9.
Ason B, Tep S, Davis HR Jr, Xu Y, Tetzloff G, Galinski B, Soriano F, Dubinina N, Zhu L, Stefanni A, Wong KK, Tadin-Strapps M, Bartz SR, Hubbard B, Ranalletta M, Sachs AB, Flanagan WM, Strack A, Kuklin NA. Ason B, et al. Among authors: tetzloff g. J Lipid Res. 2011 Apr;52(4):679-87. doi: 10.1194/jlr.M013664. Epub 2011 Jan 24. J Lipid Res. 2011. PMID: 21262787 Free PMC article.
Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.
Davis HR Jr, Zhu LJ, Hoos LM, Tetzloff G, Maguire M, Liu J, Yao X, Iyer SP, Lam MH, Lund EG, Detmers PA, Graziano MP, Altmann SW. Davis HR Jr, et al. Among authors: tetzloff g. J Biol Chem. 2004 Aug 6;279(32):33586-92. doi: 10.1074/jbc.M405817200. Epub 2004 Jun 1. J Biol Chem. 2004. PMID: 15173162 Free article.
Deficiency of Niemann-Pick C1 Like 1 prevents atherosclerosis in ApoE-/- mice.
Davis HR Jr, Hoos LM, Tetzloff G, Maguire M, Zhu LJ, Graziano MP, Altmann SW. Davis HR Jr, et al. Among authors: tetzloff g. Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):841-9. doi: 10.1161/01.ATV.0000257627.40486.46. Epub 2007 Jan 11. Arterioscler Thromb Vasc Biol. 2007. PMID: 17218600
28 results