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Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity.
Pittella F, Zhang M, Lee Y, Kim HJ, Tockary T, Osada K, Ishii T, Miyata K, Nishiyama N, Kataoka K. Pittella F, et al. Among authors: tockary t. Biomaterials. 2011 Apr;32(11):3106-14. doi: 10.1016/j.biomaterials.2010.12.057. Epub 2011 Jan 26. Biomaterials. 2011. PMID: 21272932
Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors.
Dirisala A, Osada K, Chen Q, Tockary TA, Machitani K, Osawa S, Liu X, Ishii T, Miyata K, Oba M, Uchida S, Itaka K, Kataoka K. Dirisala A, et al. Among authors: tockary ta. Biomaterials. 2014 Jul;35(20):5359-5368. doi: 10.1016/j.biomaterials.2014.03.037. Epub 2014 Apr 8. Biomaterials. 2014. PMID: 24720877
Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting.
Chen Q, Osada K, Ge Z, Uchida S, Tockary TA, Dirisala A, Matsui A, Toh K, Takeda KM, Liu X, Nomoto T, Ishii T, Oba M, Matsumoto Y, Kataoka K. Chen Q, et al. Among authors: tockary ta. Biomaterials. 2017 Jan;113:253-265. doi: 10.1016/j.biomaterials.2016.10.042. Epub 2016 Oct 28. Biomaterials. 2017. PMID: 27835820
21 results