Zhang Y - Search Results

1

Design of potent and selective GPR119 agonists for type II diabetes.

Szewczyk JW, Acton J, Adams AD, Chicchi G, Freeman S, Howard AD, Huang Y, Li C, Meinke PT, Mosely R, Murphy E, Samuel R, Santini C, Yang M, Zhang Y, Zhao K, Wood HB. Szewczyk JW, et al. Among authors: zhang y. Bioorg Med Chem Lett. 2011 May 1;21(9):2665-9. doi: 10.1016/j.bmcl.2010.12.086. Epub 2010 Dec 22. Bioorg Med Chem Lett. 2011. PMID: 21273063

2

Novel 2,3-dihydrobenzofuran-2-carboxylic acids: highly potent and subtype-selective PPARalpha agonists with potent hypolipidemic activity.

Shi GQ, Dropinski JF, Zhang Y, Santini C, Sahoo SP, Berger JP, Macnaul KL, Zhou G, Agrawal A, Alvaro R, Cai TQ, Hernandez M, Wright SD, Moller DE, Heck JV, Meinke PT. Shi GQ, et al. Among authors: zhang y. J Med Chem. 2005 Aug 25;48(17):5589-99. doi: 10.1021/jm050373g. J Med Chem. 2005. PMID: 16107159

3

Design, synthesis, and X-ray crystallographic analysis of a novel class of HIV-1 protease inhibitors.

Ganguly AK, Alluri SS, Caroccia D, Biswas D, Wang CH, Kang E, Zhang Y, McPhail AT, Carroll SS, Burlein C, Munshi V, Orth P, Strickland C. Ganguly AK, et al. Among authors: zhang y. J Med Chem. 2011 Oct 27;54(20):7176-83. doi: 10.1021/jm200778q. Epub 2011 Sep 26. J Med Chem. 2011. PMID: 21916489

4

Discovery and optimization of orally active cyclohexane-based prolylcarboxypeptidase (PrCP) inhibitors.

Debenham JS, Graham TH, Verras A, Zhang Y, Clements MJ, Kuethe JT, Madsen-Duggan C, Liu W, Bhatt UR, Chen D, Chen Q, Garcia-Calvo M, Geissler WM, He H, Li X, Lisnock J, Shen Z, Tong X, Tung EC, Wiltsie J, Xu S, Hale JJ, Pinto S, Shen DM. Debenham JS, et al. Among authors: zhang y. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6228-33. doi: 10.1016/j.bmcl.2013.09.094. Epub 2013 Oct 8. Bioorg Med Chem Lett. 2013. PMID: 24157366

5

Design and synthesis of 4-aryl-4-oxobutanoic acid amides as calpain inhibitors.

Zhang Y, Jung SY, Jin C, Kim ND, Gong P, Lee YS. Zhang Y, et al. Bioorg Med Chem Lett. 2009 Jan 15;19(2):502-7. doi: 10.1016/j.bmcl.2008.11.030. Epub 2008 Nov 14. Bioorg Med Chem Lett. 2009. PMID: 19041242

6

Discovery of a novel class anti-proliferative agents and potential inhibitors of EGFR tyrosine kinases based on 4-anilinotetrahydropyrido[4,3-d]pyrimidine scaffold: Design, synthesis and biological evaluations.

Zhang Y, Zhang K, Zhao M, Zhang L, Qin M, Guo S, Zhao Y, Gong P. Zhang Y, et al. Among authors: zhang l, zhang k. Bioorg Med Chem. 2015 Aug 1;23(15):4591-4607. doi: 10.1016/j.bmc.2015.05.059. Epub 2015 Jun 6. Bioorg Med Chem. 2015. PMID: 26122771

7

Synthesis, biological evaluation, and molecular docking studies of N-((1,3-diphenyl-1H-pyrazol-4-yl)methyl)aniline derivatives as novel anticancer agents.

Huang XF, Lu X, Zhang Y, Song GQ, He QL, Li QS, Yang XH, Wei Y, Zhu HL. Huang XF, et al. Among authors: zhang y. Bioorg Med Chem. 2012 Aug 15;20(16):4895-900. doi: 10.1016/j.bmc.2012.06.056. Epub 2012 Jul 10. Bioorg Med Chem. 2012. PMID: 22819191

8

Design and optimization of hybrid of 2,4-diaminopyrimidine and arylthiazole scaffold as anticancer cell proliferation and migration agents.

Zhou W, Huang A, Zhang Y, Lin Q, Guo W, You Z, Yi Z, Liu M, Chen Y. Zhou W, et al. Among authors: zhang y. Eur J Med Chem. 2015;96:269-80. doi: 10.1016/j.ejmech.2015.04.027. Epub 2015 Apr 13. Eur J Med Chem. 2015. PMID: 25899332

9

Synthesis, biological evaluation and molecular docking of 2-phenyl-benzo[d]oxazole-7-carboxamide derivatives as potential Staphylococcus aureus Sortase A inhibitors.

Zhang Y, Bao J, Deng XX, He W, Fan JJ, Jiang FQ, Fu L. Zhang Y, et al. Bioorg Med Chem Lett. 2016 Aug 15;26(16):4081-5. doi: 10.1016/j.bmcl.2016.06.074. Epub 2016 Jun 25. Bioorg Med Chem Lett. 2016. PMID: 27400889

10

Synthesis, biological evaluation and molecular docking analysis of 2-phenyl-benzofuran-3-carboxamide derivatives as potential inhibitors of Staphylococcus aureus Sortase A.

He W, Zhang Y, Bao J, Deng X, Batara J, Casey S, Guo Q, Jiang F, Fu L. He W, et al. Among authors: zhang y. Bioorg Med Chem. 2017 Feb 15;25(4):1341-1351. doi: 10.1016/j.bmc.2016.12.030. Epub 2016 Dec 25. Bioorg Med Chem. 2017. PMID: 28094221

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