Brown JR - Search Results

1

Computational biology approaches for selecting host-pathogen drug targets.

Brown JR, Magid-Slav M, Sanseau P, Rajpal DK. Brown JR, et al. Drug Discov Today. 2011 Mar;16(5-6):229-36. doi: 10.1016/j.drudis.2011.01.008. Epub 2011 Jan 28. Drug Discov Today. 2011. PMID: 21277381 Review.

2

Human microbial metabolites as a source of new drugs.

Saha S, Rajpal DK, Brown JR. Saha S, et al. Among authors: brown jr. Drug Discov Today. 2016 Apr;21(4):692-8. doi: 10.1016/j.drudis.2016.02.009. Epub 2016 Feb 22. Drug Discov Today. 2016. PMID: 26916596 Review.

3

A computational view of microRNAs and their targets.

Brown JR, Sanseau P. Brown JR, et al. Drug Discov Today. 2005 Apr 15;10(8):595-601. doi: 10.1016/S1359-6446(05)03399-4. Drug Discov Today. 2005. PMID: 15837603 Review.

4

Host response to respiratory bacterial pathogens as identified by integrated analysis of human gene expression data.

Smith SB, Magid-Slav M, Brown JR. Smith SB, et al. Among authors: brown jr. PLoS One. 2013 Sep 27;8(9):e75607. doi: 10.1371/journal.pone.0075607. eCollection 2013. PLoS One. 2013. PMID: 24086587 Free PMC article.

5

Modulating the human gut microbiome as an emerging therapeutic paradigm.

Rajpal DK, Brown JR. Rajpal DK, et al. Among authors: brown jr. Sci Prog. 2013;96(Pt 3):224-36. doi: 10.3184/003685013X13691404141587. Sci Prog. 2013. PMID: 24244970 Free PMC article. Review.

6

Meta-analysis of human gene expression in response to Mycobacterium tuberculosis infection reveals potential therapeutic targets.

Wang Z, Arat S, Magid-Slav M, Brown JR. Wang Z, et al. Among authors: brown jr. BMC Syst Biol. 2018 Jan 10;12(1):3. doi: 10.1186/s12918-017-0524-z. BMC Syst Biol. 2018. PMID: 29321020 Free PMC article.

7

Identification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysis.

Smith SB, Dampier W, Tozeren A, Brown JR, Magid-Slav M. Smith SB, et al. Among authors: brown jr. PLoS One. 2012;7(3):e33174. doi: 10.1371/journal.pone.0033174. Epub 2012 Mar 14. PLoS One. 2012. PMID: 22432004 Free PMC article.

8

Gut microbiome differences between metformin- and liraglutide-treated T2DM subjects.

Wang Z, Saha S, Van Horn S, Thomas E, Traini C, Sathe G, Rajpal DK, Brown JR. Wang Z, et al. Among authors: brown jr. Endocrinol Diabetes Metab. 2017 Dec 28;1(1):e00009. doi: 10.1002/edm2.9. eCollection 2018 Jan. Endocrinol Diabetes Metab. 2017. PMID: 30815546 Free PMC article.

9

Evolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugs.

Brown JR, Koretke KK, Birkeland ML, Sanseau P, Patrick DR. Brown JR, et al. BMC Evol Biol. 2004 Oct 12;4:39. doi: 10.1186/1471-2148-4-39. BMC Evol Biol. 2004. PMID: 15476560 Free PMC article.

10

Minipig and beagle animal model genomes aid species selection in pharmaceutical discovery and development.

Vamathevan JJ, Hall MD, Hasan S, Woollard PM, Xu M, Yang Y, Li X, Wang X, Kenny S, Brown JR, Huxley-Jones J, Lyon J, Haselden J, Min J, Sanseau P. Vamathevan JJ, et al. Among authors: brown jr. Toxicol Appl Pharmacol. 2013 Jul 15;270(2):149-57. doi: 10.1016/j.taap.2013.04.007. Epub 2013 Apr 19. Toxicol Appl Pharmacol. 2013. PMID: 23602889

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