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PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX.
Bray PG, Mungthin M, Hastings IM, Biagini GA, Saidu DK, Lakshmanan V, Johnson DJ, Hughes RH, Stocks PA, O'Neill PM, Fidock DA, Warhurst DC, Ward SA. Bray PG, et al. Among authors: lakshmanan v. Mol Microbiol. 2006 Oct;62(1):238-51. doi: 10.1111/j.1365-2958.2006.05368.x. Epub 2006 Aug 31. Mol Microbiol. 2006. PMID: 16956382 Free PMC article.
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.
Yu M, Kumar TR, Nkrumah LJ, Coppi A, Retzlaff S, Li CD, Kelly BJ, Moura PA, Lakshmanan V, Freundlich JS, Valderramos JC, Vilcheze C, Siedner M, Tsai JH, Falkard B, Sidhu AB, Purcell LA, Gratraud P, Kremer L, Waters AP, Schiehser G, Jacobus DP, Janse CJ, Ager A, Jacobs WR Jr, Sacchettini JC, Heussler V, Sinnis P, Fidock DA. Yu M, et al. Among authors: lakshmanan v. Cell Host Microbe. 2008 Dec 11;4(6):567-78. doi: 10.1016/j.chom.2008.11.001. Cell Host Microbe. 2008. PMID: 19064257 Free PMC article.
A non-radioactive DAPI-based high-throughput in vitro assay to assess Plasmodium falciparum responsiveness to antimalarials--increased sensitivity of P. falciparum to chloroquine in Senegal.
Ndiaye D, Patel V, Demas A, LeRoux M, Ndir O, Mboup S, Clardy J, Lakshmanan V, Daily JP, Wirth DF. Ndiaye D, et al. Among authors: lakshmanan v. Am J Trop Med Hyg. 2010 Feb;82(2):228-30. doi: 10.4269/ajtmh.2010.09-0470. Am J Trop Med Hyg. 2010. PMID: 20133997 Free PMC article.
Metabolomics and malaria biology.
Lakshmanan V, Rhee KY, Daily JP. Lakshmanan V, et al. Mol Biochem Parasitol. 2011 Feb;175(2):104-11. doi: 10.1016/j.molbiopara.2010.09.008. Epub 2010 Oct 21. Mol Biochem Parasitol. 2011. PMID: 20970461 Free PMC article. Review.
Plasmodium vivax liver stage development and hypnozoite persistence in human liver-chimeric mice.
Mikolajczak SA, Vaughan AM, Kangwanrangsan N, Roobsoong W, Fishbaugher M, Yimamnuaychok N, Rezakhani N, Lakshmanan V, Singh N, Kaushansky A, Camargo N, Baldwin M, Lindner SE, Adams JH, Sattabongkot J, Kappe SH. Mikolajczak SA, et al. Among authors: lakshmanan v. Cell Host Microbe. 2015 Apr 8;17(4):526-35. doi: 10.1016/j.chom.2015.02.011. Epub 2015 Mar 19. Cell Host Microbe. 2015. PMID: 25800544 Free PMC article.
135 results