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Page 1
Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network.
Zhang SS, Kim KH, Rosen A, Smyth JW, Sakuma R, Delgado-Olguín P, Davis M, Chi NC, Puviindran V, Gaborit N, Sukonnik T, Wylie JN, Brand-Arzamendi K, Farman GP, Kim J, Rose RA, Marsden PA, Zhu Y, Zhou YQ, Miquerol L, Henkelman RM, Stainier DY, Shaw RM, Hui CC, Bruneau BG, Backx PH. Zhang SS, et al. Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13576-81. doi: 10.1073/pnas.1106911108. Epub 2011 Aug 8. Proc Natl Acad Sci U S A. 2011. PMID: 21825130 Free PMC article.
Cardiac conduction is required to preserve cardiac chamber morphology.
Chi NC, Bussen M, Brand-Arzamendi K, Ding C, Olgin JE, Shaw RM, Martin GR, Stainier DY. Chi NC, et al. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14662-7. doi: 10.1073/pnas.0909432107. Epub 2010 Jul 30. Proc Natl Acad Sci U S A. 2010. PMID: 20675583 Free PMC article.
Cse1l is a negative regulator of CFTR-dependent fluid secretion.
Bagnat M, Navis A, Herbstreith S, Brand-Arzamendi K, Curado S, Gabriel S, Mostov K, Huisken J, Stainier DY. Bagnat M, et al. Curr Biol. 2010 Oct 26;20(20):1840-5. doi: 10.1016/j.cub.2010.09.012. Epub 2010 Oct 7. Curr Biol. 2010. PMID: 20933420 Free PMC article.
Zebrafish hhatla is involved in cardiac hypertrophy.
Shi X, Zhang Y, Gong Y, Chen M, Brand-Arzamendi K, Liu X, Wen XY. Shi X, et al. Among authors: brand arzamendi k. J Cell Physiol. 2021 May;236(5):3700-3709. doi: 10.1002/jcp.30106. Epub 2020 Oct 14. J Cell Physiol. 2021. PMID: 33052609
Sialic acid catabolism by N-acetylneuraminate pyruvate lyase is essential for muscle function.
Wen XY, Tarailo-Graovac M, Brand-Arzamendi K, Willems A, Rakic B, Huijben K, Da Silva A, Pan X, El-Rass S, Ng R, Selby K, Philip AM, Yun J, Ye XC, Ross CJ, Lehman AM, Zijlstra F, Abu Bakar N, Drögemöller B, Moreland J, Wasserman WW, Vallance H, van Scherpenzeel M, Karbassi F, Hoskings M, Engelke U, de Brouwer A, Wevers RA, Pshezhetsky AV, van Karnebeek CD, Lefeber DJ. Wen XY, et al. Among authors: brand arzamendi k. JCI Insight. 2018 Dec 20;3(24):e122373. doi: 10.1172/jci.insight.122373. JCI Insight. 2018. PMID: 30568043 Free PMC article.
Bi-allelic GOT2 Mutations Cause a Treatable Malate-Aspartate Shuttle-Related Encephalopathy.
van Karnebeek CDM, Ramos RJ, Wen XY, Tarailo-Graovac M, Gleeson JG, Skrypnyk C, Brand-Arzamendi K, Karbassi F, Issa MY, van der Lee R, Drögemöller BI, Koster J, Rousseau J, Campeau PM, Wang Y, Cao F, Li M, Ruiter J, Ciapaite J, Kluijtmans LAJ, Willemsen MAAP, Jans JJ, Ross CJ, Wintjes LT, Rodenburg RJ, Huigen MCDG, Jia Z, Waterham HR, Wasserman WW, Wanders RJA, Verhoeven-Duif NM, Zaki MS, Wevers RA. van Karnebeek CDM, et al. Among authors: brand arzamendi k. Am J Hum Genet. 2019 Sep 5;105(3):534-548. doi: 10.1016/j.ajhg.2019.07.015. Epub 2019 Aug 15. Am J Hum Genet. 2019. PMID: 31422819 Free PMC article.
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