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Integrin α5β1 and p53 convergent pathways in the control of anti-apoptotic proteins PEA-15 and survivin in high-grade glioma.
Renner G, Janouskova H, Noulet F, Koenig V, Guerin E, Bär S, Nuesch J, Rechenmacher F, Neubauer S, Kessler H, Blandin AF, Choulier L, Etienne-Selloum N, Lehmann M, Lelong-Rebel I, Martin S, Dontenwill M. Renner G, et al. Among authors: noulet f. Cell Death Differ. 2016 Apr;23(4):640-53. doi: 10.1038/cdd.2015.131. Epub 2015 Oct 16. Cell Death Differ. 2016. PMID: 26470725 Free PMC article.
Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma.
Janouskova H, Maglott A, Leger DY, Bossert C, Noulet F, Guerin E, Guenot D, Pinel S, Chastagner P, Plenat F, Entz-Werle N, Lehmann-Che J, Godet J, Martin S, Teisinger J, Dontenwill M. Janouskova H, et al. Among authors: noulet f. Cancer Res. 2012 Jul 15;72(14):3463-70. doi: 10.1158/0008-5472.CAN-11-4199. Epub 2012 May 16. Cancer Res. 2012. PMID: 22593187
Single cell tracking assay reveals an opposite effect of selective small non-peptidic α5β1 or αvβ3/β5 integrin antagonists in U87MG glioma cells.
Ray AM, Schaffner F, Janouskova H, Noulet F, Rognan D, Lelong-Rebel I, Choulier L, Blandin AF, Lehmann M, Martin S, Kapp T, Neubauer S, Rechenmacher F, Kessler H, Dontenwill M. Ray AM, et al. Among authors: noulet f. Biochim Biophys Acta. 2014 Sep;1840(9):2978-87. doi: 10.1016/j.bbagen.2014.04.024. Epub 2014 May 5. Biochim Biophys Acta. 2014. PMID: 24810979
19 results