D'Hooge R - Search Results

1

Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant.

Sydow A, Van der Jeugd A, Zheng F, Ahmed T, Balschun D, Petrova O, Drexler D, Zhou L, Rune G, Mandelkow E, D'Hooge R, Alzheimer C, Mandelkow EM. Sydow A, et al. J Neurosci. 2011 Feb 16;31(7):2511-25. doi: 10.1523/JNEUROSCI.5245-10.2011. J Neurosci. 2011. PMID: 21325519 Free PMC article.

2

Reversibility of Tau-related cognitive defects in a regulatable FTD mouse model.

Sydow A, Van der Jeugd A, Zheng F, Ahmed T, Balschun D, Petrova O, Drexler D, Zhou L, Rune G, Mandelkow E, D'Hooge R, Alzheimer C, Mandelkow EM. Sydow A, et al. J Mol Neurosci. 2011 Nov;45(3):432-7. doi: 10.1007/s12031-011-9604-5. Epub 2011 Aug 6. J Mol Neurosci. 2011. PMID: 21822709

3

Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau.

Van der Jeugd A, Hochgräfe K, Ahmed T, Decker JM, Sydow A, Hofmann A, Wu D, Messing L, Balschun D, D'Hooge R, Mandelkow EM. Van der Jeugd A, et al. Acta Neuropathol. 2012 Jun;123(6):787-805. doi: 10.1007/s00401-012-0987-3. Epub 2012 Apr 25. Acta Neuropathol. 2012. PMID: 22532069 Free PMC article.

4

Neurocognitive and psychotiform behavioral alterations and enhanced hippocampal long-term potentiation in transgenic mice displaying neuropathological features of human alpha-mannosidosis.

D'Hooge R, Lüllmann-Rauch R, Beckers T, Balschun D, Schwake M, Reiss K, von Figura K, Saftig P. D'Hooge R, et al. J Neurosci. 2005 Jul 13;25(28):6539-49. doi: 10.1523/JNEUROSCI.0283-05.2005. J Neurosci. 2005. PMID: 16014715 Free PMC article.

5

Spred1 is required for synaptic plasticity and hippocampus-dependent learning.

Denayer E, Ahmed T, Brems H, Van Woerden G, Borgesius NZ, Callaerts-Vegh Z, Yoshimura A, Hartmann D, Elgersma Y, D'Hooge R, Legius E, Balschun D. Denayer E, et al. J Neurosci. 2008 Dec 31;28(53):14443-9. doi: 10.1523/JNEUROSCI.4698-08.2008. J Neurosci. 2008. PMID: 19118178 Free PMC article.

6

Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission.

Van der Jeugd A, Ahmed T, Burnouf S, Belarbi K, Hamdame M, Grosjean ME, Humez S, Balschun D, Blum D, Buée L, D'Hooge R. Van der Jeugd A, et al. Neurobiol Learn Mem. 2011 Mar;95(3):296-304. doi: 10.1016/j.nlm.2010.12.005. Epub 2010 Dec 16. Neurobiol Learn Mem. 2011. PMID: 21167950

7

Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion.

Ahmed T, Van der Jeugd A, Blum D, Galas MC, D'Hooge R, Buee L, Balschun D. Ahmed T, et al. Neurobiol Aging. 2014 Nov;35(11):2474-2478. doi: 10.1016/j.neurobiolaging.2014.05.005. Epub 2014 May 10. Neurobiol Aging. 2014. PMID: 24913895

8

Rescue of impaired late-phase long-term depression in a tau transgenic mouse model.

Ahmed T, Blum D, Burnouf S, Demeyer D, Buée-Scherrer V, D'Hooge R, Buée L, Balschun D. Ahmed T, et al. Neurobiol Aging. 2015 Feb;36(2):730-9. doi: 10.1016/j.neurobiolaging.2014.09.015. Epub 2014 Sep 28. Neurobiol Aging. 2015. PMID: 25443285

9

An N-methyl-D-aspartate-receptor dependent, late-phase long-term depression in middle-aged mice identifies no GluN2-subunit bias.

Ahmed T, Sabanov V, D'Hooge R, Balschun D. Ahmed T, et al. Neuroscience. 2011 Jun 30;185:27-38. doi: 10.1016/j.neuroscience.2011.04.006. Epub 2011 Apr 12. Neuroscience. 2011. PMID: 21504782

10

Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions.

Prox J, Bernreuther C, Altmeppen H, Grendel J, Glatzel M, D'Hooge R, Stroobants S, Ahmed T, Balschun D, Willem M, Lammich S, Isbrandt D, Schweizer M, Horré K, De Strooper B, Saftig P. Prox J, et al. J Neurosci. 2013 Aug 7;33(32):12915-28, 12928a. doi: 10.1523/JNEUROSCI.5910-12.2013. J Neurosci. 2013. PMID: 23926248 Free PMC article.

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