Miyata Y - Search Results

1

Chemical screens against a reconstituted multiprotein complex: myricetin blocks DnaJ regulation of DnaK through an allosteric mechanism.

Chang L, Miyata Y, Ung PM, Bertelsen EB, McQuade TJ, Carlson HA, Zuiderweg ER, Gestwicki JE. Chang L, et al. Among authors: miyata y. Chem Biol. 2011 Feb 25;18(2):210-21. doi: 10.1016/j.chembiol.2010.12.010. Chem Biol. 2011. PMID: 21338918 Free PMC article.

2

Pharmacological targeting of the Hsp70 chaperone.

Patury S, Miyata Y, Gestwicki JE. Patury S, et al. Among authors: miyata y. Curr Top Med Chem. 2009;9(15):1337-51. doi: 10.2174/156802609789895674. Curr Top Med Chem. 2009. PMID: 19860737 Free PMC article. Review.

3

High-throughput screen for Escherichia coli heat shock protein 70 (Hsp70/DnaK): ATPase assay in low volume by exploiting energy transfer.

Miyata Y, Chang L, Bainor A, McQuade TJ, Walczak CP, Zhang Y, Larsen MJ, Kirchhoff P, Gestwicki JE. Miyata Y, et al. J Biomol Screen. 2010 Dec;15(10):1211-9. doi: 10.1177/1087057110380571. Epub 2010 Oct 6. J Biomol Screen. 2010. PMID: 20926844 Free PMC article.

4

Allosteric drugs: the interaction of antitumor compound MKT-077 with human Hsp70 chaperones.

Rousaki A, Miyata Y, Jinwal UK, Dickey CA, Gestwicki JE, Zuiderweg ER. Rousaki A, et al. Among authors: miyata y. J Mol Biol. 2011 Aug 19;411(3):614-32. doi: 10.1016/j.jmb.2011.06.003. Epub 2011 Jun 25. J Mol Biol. 2011. PMID: 21708173 Free PMC article.

5

Cysteine reactivity distinguishes redox sensing by the heat-inducible and constitutive forms of heat shock protein 70.

Miyata Y, Rauch JN, Jinwal UK, Thompson AD, Srinivasan S, Dickey CA, Gestwicki JE. Miyata Y, et al. Chem Biol. 2012 Nov 21;19(11):1391-9. doi: 10.1016/j.chembiol.2012.07.026. Chem Biol. 2012. PMID: 23177194 Free PMC article.

6

Molecular chaperones and regulation of tau quality control: strategies for drug discovery in tauopathies.

Miyata Y, Koren J, Kiray J, Dickey CA, Gestwicki JE. Miyata Y, et al. Future Med Chem. 2011 Sep;3(12):1523-37. doi: 10.4155/fmc.11.88. Future Med Chem. 2011. PMID: 21882945 Free PMC article. Review.

7

Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation.

Wang AM, Miyata Y, Klinedinst S, Peng HM, Chua JP, Komiyama T, Li X, Morishima Y, Merry DE, Pratt WB, Osawa Y, Collins CA, Gestwicki JE, Lieberman AP. Wang AM, et al. Among authors: miyata y. Nat Chem Biol. 2013 Feb;9(2):112-8. doi: 10.1038/nchembio.1140. Epub 2012 Dec 9. Nat Chem Biol. 2013. PMID: 23222885 Free PMC article.

8

Facilitating Akt clearance via manipulation of Hsp70 activity and levels.

Koren J 3rd, Jinwal UK, Jin Y, O'Leary J, Jones JR, Johnson AG, Blair LJ, Abisambra JF, Chang L, Miyata Y, Cheng AM, Guo J, Cheng JQ, Gestwicki JE, Dickey CA. Koren J 3rd, et al. Among authors: miyata y. J Biol Chem. 2010 Jan 22;285(4):2498-505. doi: 10.1074/jbc.M109.057208. Epub 2009 Nov 4. J Biol Chem. 2010. PMID: 19889640 Free PMC article.

9

Heme-dependent activation of neuronal nitric oxide synthase by cytosol is due to an Hsp70-dependent, thioredoxin-mediated thiol-disulfide interchange in the heme/substrate binding cleft.

Morishima Y, Lau M, Peng HM, Miyata Y, Gestwicki JE, Pratt WB, Osawa Y. Morishima Y, et al. Among authors: miyata y. Biochemistry. 2011 Aug 23;50(33):7146-56. doi: 10.1021/bi200751t. Epub 2011 Jul 21. Biochemistry. 2011. PMID: 21755988 Free PMC article.

10

Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels.

Miyata Y, Li X, Lee HF, Jinwal UK, Srinivasan SR, Seguin SP, Young ZT, Brodsky JL, Dickey CA, Sun D, Gestwicki JE. Miyata Y, et al. ACS Chem Neurosci. 2013 Jun 19;4(6):930-9. doi: 10.1021/cn300210g. Epub 2013 Mar 20. ACS Chem Neurosci. 2013. PMID: 23472668 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,495 results

Search Page

Filters