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Evidence for an association between compound heterozygosity for germ line mutations in the hemochromatosis (HFE) gene and increased risk of colorectal cancer.
Robinson JP, Johnson VL, Rogers PA, Houlston RS, Maher ER, Bishop DT, Evans DG, Thomas HJ, Tomlinson IP, Silver AR. Robinson JP, et al. Among authors: silver ar. Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1460-3. doi: 10.1158/1055-9965.EPI-04-0672. Cancer Epidemiol Biomarkers Prev. 2005. PMID: 15941956
Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation.
Sieber OM, Segditsas S, Knudsen AL, Zhang J, Luz J, Rowan AJ, Spain SL, Thirlwell C, Howarth KM, Jaeger EE, Robinson J, Volikos E, Silver A, Kelly G, Aretz S, Frayling I, Hutter P, Dunlop M, Guenther T, Neale K, Phillips R, Heinimann K, Tomlinson IP. Sieber OM, et al. Among authors: silver a. Gut. 2006 Oct;55(10):1440-8. doi: 10.1136/gut.2005.087106. Epub 2006 Feb 4. Gut. 2006. PMID: 16461775 Free PMC article.
LKB1 exonic and whole gene deletions are a common cause of Peutz-Jeghers syndrome.
Volikos E, Robinson J, Aittomäki K, Mecklin JP, Järvinen H, Westerman AM, de Rooji FW, Vogel T, Moeslein G, Launonen V, Tomlinson IP, Silver AR, Aaltonen LA. Volikos E, et al. Among authors: silver ar. J Med Genet. 2006 May;43(5):e18. doi: 10.1136/jmg.2005.039875. J Med Genet. 2006. PMID: 16648371 Free PMC article.
Molecular classification and genetic pathways in hyperplastic polyposis syndrome.
Carvajal-Carmona LG, Howarth KM, Lockett M, Polanco-Echeverry GM, Volikos E, Gorman M, Barclay E, Martin L, Jones AM, Saunders B, Guenther T, Donaldson A, Paterson J, Frayling I, Novelli MR, Phillips R, Thomas HJ, Silver A, Atkin W, Tomlinson IP. Carvajal-Carmona LG, et al. Among authors: silver a. J Pathol. 2007 Aug;212(4):378-85. doi: 10.1002/path.2187. J Pathol. 2007. PMID: 17503413
Apc mice: models, modifiers and mutants.
McCart AE, Vickaryous NK, Silver A. McCart AE, et al. Among authors: silver a. Pathol Res Pract. 2008;204(7):479-90. doi: 10.1016/j.prp.2008.03.004. Epub 2008 Jun 5. Pathol Res Pract. 2008. PMID: 18538487 Review.
702 results