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Transcriptional control of adipose lipid handling by IRF4.
Eguchi J, Wang X, Yu S, Kershaw EE, Chiu PC, Dushay J, Estall JL, Klein U, Maratos-Flier E, Rosen ED. Eguchi J, et al. Among authors: wang x. Cell Metab. 2011 Mar 2;13(3):249-59. doi: 10.1016/j.cmet.2011.02.005. Cell Metab. 2011. PMID: 21356515 Free PMC article.
IRF4 is a key thermogenic transcriptional partner of PGC-1α.
Kong X, Banks A, Liu T, Kazak L, Rao RR, Cohen P, Wang X, Yu S, Lo JC, Tseng YH, Cypess AM, Xue R, Kleiner S, Kang S, Spiegelman BM, Rosen ED. Kong X, et al. Among authors: wang x. Cell. 2014 Jul 3;158(1):69-83. doi: 10.1016/j.cell.2014.04.049. Cell. 2014. PMID: 24995979 Free PMC article.
IRF3 promotes adipose inflammation and insulin resistance and represses browning.
Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, Tenen D, Roh HC, Kong X, Kazak L, Ahmad R, Rosen ED. Kumari M, et al. Among authors: wang x. J Clin Invest. 2016 Aug 1;126(8):2839-54. doi: 10.1172/JCI86080. Epub 2016 Jul 11. J Clin Invest. 2016. PMID: 27400129 Free PMC article.
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