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The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon.
Alvarez-Breckenridge CA, Yu J, Price R, Wei M, Wang Y, Nowicki MO, Ha YP, Bergin S, Hwang C, Fernandez SA, Kaur B, Caligiuri MA, Chiocca EA. Alvarez-Breckenridge CA, et al. J Virol. 2012 Apr;86(8):4566-77. doi: 10.1128/JVI.05545-11. Epub 2012 Feb 8. J Virol. 2012. PMID: 22318143 Free PMC article.
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors.
Alvarez-Breckenridge CA, Yu J, Price R, Wojton J, Pradarelli J, Mao H, Wei M, Wang Y, He S, Hardcastle J, Fernandez SA, Kaur B, Lawler SE, Vivier E, Mandelboim O, Moretta A, Caligiuri MA, Chiocca EA. Alvarez-Breckenridge CA, et al. Nat Med. 2012 Dec;18(12):1827-34. doi: 10.1038/nm.3013. Epub 2012 Nov 25. Nat Med. 2012. PMID: 23178246 Free PMC article.
MicroRNAs activate natural killer cells through Toll-like receptor signaling.
He S, Chu J, Wu LC, Mao H, Peng Y, Alvarez-Breckenridge CA, Hughes T, Wei M, Zhang J, Yuan S, Sandhu S, Vasu S, Benson DM Jr, Hofmeister CC, He X, Ghoshal K, Devine SM, Caligiuri MA, Yu J. He S, et al. Blood. 2013 Jun 6;121(23):4663-71. doi: 10.1182/blood-2012-07-441360. Epub 2013 Apr 11. Blood. 2013. PMID: 23580661 Free PMC article.
BAI1 Orchestrates Macrophage Inflammatory Response to HSV Infection-Implications for Oncolytic Viral Therapy.
Bolyard C, Meisen WH, Banasavadi-Siddegowda Y, Hardcastle J, Yoo JY, Wohleb ES, Wojton J, Yu JG, Dubin S, Khosla M, Xu B, Smith J, Alvarez-Breckenridge C, Pow-Anpongkul P, Pichiorri F, Zhang J, Old M, Zhu D, Van Meir EG, Godbout JP, Caligiuri MA, Yu J, Kaur B. Bolyard C, et al. Clin Cancer Res. 2017 Apr 1;23(7):1809-1819. doi: 10.1158/1078-0432.CCR-16-1818. Epub 2016 Nov 9. Clin Cancer Res. 2017. PMID: 27852701 Free PMC article.
Advances in oncolytic virus therapy for glioma.
Haseley A, Alvarez-Breckenridge C, Chaudhury AR, Kaur B. Haseley A, et al. Recent Pat CNS Drug Discov. 2009 Jan;4(1):1-13. doi: 10.2174/157488909787002573. Recent Pat CNS Drug Discov. 2009. PMID: 19149710 Free PMC article. Review.
Pharmacologic and chemical adjuvants in tumor virotherapy.
Alvarez-Breckenridge C, Kaur B, Chiocca EA. Alvarez-Breckenridge C, et al. Chem Rev. 2009 Jul;109(7):3125-40. doi: 10.1021/cr900048k. Chem Rev. 2009. PMID: 19462957 Free PMC article. Review. No abstract available.
63 results