Davis P - Search Results

1

Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies.

Yamamoto T, Nair P, Largent-Milnes TM, Jacobsen NE, Davis P, Ma SW, Yamamura HI, Vanderah TW, Porreca F, Lai J, Hruby VJ. Yamamoto T, et al. Among authors: davis p. J Med Chem. 2011 Apr 14;54(7):2029-38. doi: 10.1021/jm101023r. Epub 2011 Mar 2. J Med Chem. 2011. PMID: 21366266 Free PMC article.

2

Synthesis and biological evaluation of new biphalin analogues with non-hydrazine linkers.

Mollica A, Davis P, Ma SW, Lai J, Porreca F, Hruby VJ. Mollica A, et al. Among authors: davis p. Bioorg Med Chem Lett. 2005 May 16;15(10):2471-5. doi: 10.1016/j.bmcl.2005.03.067. Bioorg Med Chem Lett. 2005. PMID: 15863299

3

Synthesis and biological activity of the first cyclic biphalin analogues.

Mollica A, Davis P, Ma SW, Porreca F, Lai J, Hruby VJ. Mollica A, et al. Among authors: davis p. Bioorg Med Chem Lett. 2006 Jan 15;16(2):367-72. doi: 10.1016/j.bmcl.2005.09.080. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275086

4

Design and synthesis of novel hydrazide-linked bifunctional peptides as delta/mu opioid receptor agonists and CCK-1/CCK-2 receptor antagonists.

Lee YS, Agnes RS, Badghisi H, Davis P, Ma SW, Lai J, Porreca F, Hruby VJ. Lee YS, et al. Among authors: davis p. J Med Chem. 2006 Mar 9;49(5):1773-80. doi: 10.1021/jm050851n. J Med Chem. 2006. PMID: 16509592 Free PMC article.

5

Structure-activity relationships of bifunctional peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors.

Agnes RS, Lee YS, Davis P, Ma SW, Badghisi H, Porreca F, Lai J, Hruby VJ. Agnes RS, et al. Among authors: davis p. J Med Chem. 2006 May 18;49(10):2868-75. doi: 10.1021/jm050921q. J Med Chem. 2006. PMID: 16686530 Free PMC article.

6

Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity.

Petrov RR, Vardanyan RS, Lee YS, Ma SW, Davis P, Begay LJ, Lai JY, Porreca F, Hruby VJ. Petrov RR, et al. Among authors: davis p. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4946-50. doi: 10.1016/j.bmcl.2006.06.040. Epub 2006 Jul 7. Bioorg Med Chem Lett. 2006. PMID: 16828552 Free PMC article.

7

Partial retro-inverso, retro, and inverso modifications of hydrazide linked bifunctional peptides for opioid and cholecystokinin (CCK) receptors.

Lee YS, Agnes RS, Davis P, Ma SW, Badghisi H, Lai J, Porreca F, Hruby VJ. Lee YS, et al. Among authors: davis p. J Med Chem. 2007 Jan 11;50(1):165-8. doi: 10.1021/jm061268p. J Med Chem. 2007. PMID: 17201419 Free PMC article.

8

Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at mu and delta opioid receptors.

Lee YS, Nyberg J, Moye S, Agnes RS, Davis P, Ma SW, Lai J, Porreca F, Vardanyan R, Hruby VJ. Lee YS, et al. Among authors: davis p. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2161-5. doi: 10.1016/j.bmcl.2007.01.114. Epub 2007 Feb 8. Bioorg Med Chem Lett. 2007. PMID: 17329100 Free PMC article.

9

Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists.

Yamamoto T, Nair P, Davis P, Ma SW, Navratilova E, Moye S, Tumati S, Lai J, Vanderah TW, Yamamura HI, Porreca F, Hruby VJ. Yamamoto T, et al. Among authors: davis p. J Med Chem. 2007 Jun 14;50(12):2779-86. doi: 10.1021/jm061369n. Epub 2007 May 22. J Med Chem. 2007. PMID: 17516639 Free PMC article.

10

Synthesis of stable and potent delta/mu opioid peptides: analogues of H-Tyr-c[D-Cys-Gly-Phe-D-Cys]-OH by ring-closing metathesis.

Mollica A, Guardiani G, Davis P, Ma SW, Porreca F, Lai J, Mannina L, Sobolev AP, Hruby VJ. Mollica A, et al. Among authors: davis p. J Med Chem. 2007 Jun 28;50(13):3138-42. doi: 10.1021/jm061048b. Epub 2007 Jun 1. J Med Chem. 2007. PMID: 17539621 Free PMC article.

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