Huang DC - Search Results

1

Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activity.

Sleebs BE, Czabotar PE, Fairbrother WJ, Fairlie WD, Flygare JA, Huang DC, Kersten WJ, Koehler MF, Lessene G, Lowes K, Parisot JP, Smith BJ, Smith ML, Souers AJ, Street IP, Yang H, Baell JB. Sleebs BE, et al. Among authors: huang dc. J Med Chem. 2011 Mar 24;54(6):1914-26. doi: 10.1021/jm101596e. Epub 2011 Mar 2. J Med Chem. 2011. PMID: 21366295

2

Bim: a novel member of the Bcl-2 family that promotes apoptosis.

O'Connor L, Strasser A, O'Reilly LA, Hausmann G, Adams JM, Cory S, Huang DC. O'Connor L, et al. Among authors: huang dc. EMBO J. 1998 Jan 15;17(2):384-95. doi: 10.1093/emboj/17.2.384. EMBO J. 1998. PMID: 9430630 Free PMC article.

3

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex.

Puthalakath H, Huang DC, O'Reilly LA, King SM, Strasser A. Puthalakath H, et al. Among authors: huang dc. Mol Cell. 1999 Mar;3(3):287-96. doi: 10.1016/s1097-2765(00)80456-6. Mol Cell. 1999. PMID: 10198631 Free article.

4

Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs.

Baell JB, Huang DC. Baell JB, et al. Among authors: huang dc. Biochem Pharmacol. 2002 Sep;64(5-6):851-63. doi: 10.1016/s0006-2952(02)01148-6. Biochem Pharmacol. 2002. PMID: 12213579 Review.

5

The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity.

Hinds MG, Lackmann M, Skea GL, Harrison PJ, Huang DC, Day CL. Hinds MG, et al. Among authors: huang dc. EMBO J. 2003 Apr 1;22(7):1497-507. doi: 10.1093/emboj/cdg144. EMBO J. 2003. PMID: 12660157 Free PMC article.

6

Bfk: a novel weakly proapoptotic member of the Bcl-2 protein family with a BH3 and a BH2 region.

Coultas L, Pellegrini M, Visvader JE, Lindeman GJ, Chen L, Adams JM, Huang DC, Strasser A. Coultas L, et al. Among authors: huang dc. Cell Death Differ. 2003 Feb;10(2):185-92. doi: 10.1038/sj.cdd.4401204. Cell Death Differ. 2003. PMID: 12700646

7

Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity.

Wilson-Annan J, O'Reilly LA, Crawford SA, Hausmann G, Beaumont JG, Parma LP, Chen L, Lackmann M, Lithgow T, Hinds MG, Day CL, Adams JM, Huang DC. Wilson-Annan J, et al. Among authors: huang dc. J Cell Biol. 2003 Sep 1;162(5):877-87. doi: 10.1083/jcb.200302144. J Cell Biol. 2003. PMID: 12952938 Free PMC article.

8

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.

Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM, Huang DC. Chen L, et al. Among authors: huang dc. Mol Cell. 2005 Feb 4;17(3):393-403. doi: 10.1016/j.molcel.2004.12.030. Mol Cell. 2005. PMID: 15694340 Free article.

9

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.

Willis SN, Chen L, Dewson G, Wei A, Naik E, Fletcher JI, Adams JM, Huang DC. Willis SN, et al. Among authors: huang dc. Genes Dev. 2005 Jun 1;19(11):1294-305. doi: 10.1101/gad.1304105. Epub 2005 May 18. Genes Dev. 2005. PMID: 15901672 Free PMC article.

10

CED-4 forms a 2 : 2 heterotetrameric complex with CED-9 until specifically displaced by EGL-1 or CED-13.

Fairlie WD, Perugini MA, Kvansakul M, Chen L, Huang DC, Colman PM. Fairlie WD, et al. Among authors: huang dc. Cell Death Differ. 2006 Mar;13(3):426-34. doi: 10.1038/sj.cdd.4401762. Cell Death Differ. 2006. PMID: 16167070

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

301 results

Search Page

Filters