Velmourougane G - Search Results

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Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the S1 pocket of the essential malaria M1 metalloaminopeptidase.

Velmourougane G, Harbut MB, Dalal S, McGowan S, Oellig CA, Meinhardt N, Whisstock JC, Klemba M, Greenbaum DC. Velmourougane G, et al. J Med Chem. 2011 Mar 24;54(6):1655-66. doi: 10.1021/jm101227t. Epub 2011 Mar 2. J Med Chem. 2011. PMID: 21366301 Free PMC article.

Development of bestatin-based activity-based probes for metallo-aminopeptidases.

Harbut MB, Velmourougane G, Reiss G, Chandramohanadas R, Greenbaum DC. Harbut MB, et al. Among authors: velmourougane g. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5932-6. doi: 10.1016/j.bmcl.2008.09.021. Epub 2008 Sep 10. Bioorg Med Chem Lett. 2008. PMID: 18823778 Free PMC article.

Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases.

Harbut MB, Velmourougane G, Dalal S, Reiss G, Whisstock JC, Onder O, Brisson D, McGowan S, Klemba M, Greenbaum DC. Harbut MB, et al. Among authors: velmourougane g. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):E526-34. doi: 10.1073/pnas.1105601108. Epub 2011 Aug 15. Proc Natl Acad Sci U S A. 2011. PMID: 21844374 Free PMC article.

Apicomplexan parasites co-opt host calpains to facilitate their escape from infected cells.

Chandramohanadas R, Davis PH, Beiting DP, Harbut MB, Darling C, Velmourougane G, Lee MY, Greer PA, Roos DS, Greenbaum DC. Chandramohanadas R, et al. Among authors: velmourougane g. Science. 2009 May 8;324(5928):794-7. doi: 10.1126/science.1171085. Epub 2009 Apr 2. Science. 2009. PMID: 19342550 Free PMC article.

Synthesis and evaluation of an acyl-chain unsaturated analog of the Th2 biasing, immunostimulatory glycolipid, OCH.

Velmourougane G, Raju R, Bricard G, Im JS, Besra GS, Porcelli SA, Howell AR. Velmourougane G, et al. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3386-8. doi: 10.1016/j.bmcl.2009.05.042. Epub 2009 May 18. Bioorg Med Chem Lett. 2009. PMID: 19481452 Free PMC article.

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