Kehoe P - Search Results

1

Neprilysin protects against cerebral amyloid angiopathy and Aβ-induced degeneration of cerebrovascular smooth muscle cells.

Miners JS, Kehoe P, Love S. Miners JS, et al. Among authors: kehoe p. Brain Pathol. 2011 Sep;21(5):594-605. doi: 10.1111/j.1750-3639.2011.00486.x. Epub 2011 Apr 3. Brain Pathol. 2011. PMID: 21382117 Free PMC article.

2

Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy.

Miners JS, Van Helmond Z, Chalmers K, Wilcock G, Love S, Kehoe PG. Miners JS, et al. J Neuropathol Exp Neurol. 2006 Oct;65(10):1012-21. doi: 10.1097/01.jnen.0000240463.87886.9a. J Neuropathol Exp Neurol. 2006. PMID: 17021406

3

Immunocapture-based fluorometric assay for the measurement of neprilysin-specific enzyme activity in brain tissue homogenates and cerebrospinal fluid.

Miners JS, Verbeek MM, Rikkert MO, Kehoe PG, Love S. Miners JS, et al. J Neurosci Methods. 2008 Jan 30;167(2):229-36. doi: 10.1016/j.jneumeth.2007.08.012. Epub 2007 Aug 25. J Neurosci Methods. 2008. PMID: 17904641

4

Immunocapture-based fluorometric assay for the measurement of insulin-degrading enzyme activity in brain tissue homogenates.

Miners JS, Kehoe PG, Love S. Miners JS, et al. J Neurosci Methods. 2008 Mar 30;169(1):177-81. doi: 10.1016/j.jneumeth.2007.12.003. Epub 2007 Dec 17. J Neurosci Methods. 2008. PMID: 18221786

5

Insights into the pathogenesis and pathogenicity of cerebral amyloid angiopathy.

Love S, Miners S, Palmer J, Chalmers K, Kehoe P. Love S, et al. Among authors: kehoe p. Front Biosci (Landmark Ed). 2009 Jan 1;14(12):4778-92. doi: 10.2741/3567. Front Biosci (Landmark Ed). 2009. PMID: 19273389 Free article. Review.

6

Neprilysin and insulin-degrading enzyme levels are increased in Alzheimer disease in relation to disease severity.

Miners JS, Baig S, Tayler H, Kehoe PG, Love S. Miners JS, et al. J Neuropathol Exp Neurol. 2009 Aug;68(8):902-14. doi: 10.1097/NEN.0b013e3181afe475. J Neuropathol Exp Neurol. 2009. PMID: 19606063

7

Accumulation of insoluble amyloid-β in down's syndrome is associated with increased BACE-1 and neprilysin activities.

Miners JS, Morris S, Love S, Kehoe PG. Miners JS, et al. J Alzheimers Dis. 2011;23(1):101-8. doi: 10.3233/JAD-2010-101395. J Alzheimers Dis. 2011. PMID: 20930275

8

Aβ-degrading enzymes: potential for treatment of Alzheimer disease.

Miners JS, Barua N, Kehoe PG, Gill S, Love S. Miners JS, et al. J Neuropathol Exp Neurol. 2011 Nov;70(11):944-59. doi: 10.1097/NEN.0b013e3182345e46. J Neuropathol Exp Neurol. 2011. PMID: 22002425 Review.

9

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.

Hamilton G, Killick R; Genetic and Environmental Risk for Alzheimer's Disease Consortium; Translational Genomics Research Institute Consortium; Lambert JC, Amouyel P; European Alzheimer Disease Initiative; Carrasquillo MM, Pankratz VS, Graff-Radford NR, Dickson DW, Petersen RC, Younkin SG, Powell JF, Wade-Martins R. Hamilton G, et al. Neurobiol Aging. 2012 Aug;33(8):1848.e1-13. doi: 10.1016/j.neurobiolaging.2012.02.005. Epub 2012 Mar 8. Neurobiol Aging. 2012. PMID: 22405046 Free PMC article.

10

The branched-chain aminotransferase proteins: novel redox chaperones for protein disulfide isomerase--implications in Alzheimer's disease.

El Hindy M, Hezwani M, Corry D, Hull J, El Amraoui F, Harris M, Lee C, Forshaw T, Wilson A, Mansbridge A, Hassler M, Patel VB, Kehoe PG, Love S, Conway ME. El Hindy M, et al. Antioxid Redox Signal. 2014 Jun 1;20(16):2497-513. doi: 10.1089/ars.2012.4869. Epub 2013 Dec 21. Antioxid Redox Signal. 2014. PMID: 24094038 Free PMC article.

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