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Prediction of the overall renal tubular secretion and hepatic clearance of anionic drugs and a renal drug-drug interaction involving organic anion transporter 3 in humans by in vitro uptake experiments.
Watanabe T, Kusuhara H, Watanabe T, Debori Y, Maeda K, Kondo T, Nakayama H, Horita S, Ogilvie BW, Parkinson A, Hu Z, Sugiyama Y. Watanabe T, et al. Among authors: sugiyama y. Drug Metab Dispos. 2011 Jun;39(6):1031-8. doi: 10.1124/dmd.110.036129. Epub 2011 Mar 7. Drug Metab Dispos. 2011. PMID: 21383204
Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2).
Sasaki M, Suzuki H, Ito K, Abe T, Sugiyama Y. Sasaki M, et al. Among authors: sugiyama y. J Biol Chem. 2002 Feb 22;277(8):6497-503. doi: 10.1074/jbc.M109081200. Epub 2001 Dec 17. J Biol Chem. 2002. PMID: 11748225 Free article.
2,701 results