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SorLA regulates the activity of lipoprotein lipase by intracellular trafficking.
Klinger SC, Glerup S, Raarup MK, Mari MC, Nyegaard M, Koster G, Prabakaran T, Nilsson SK, Kjaergaard MM, Bakke O, Nykjær A, Olivecrona G, Petersen CM, Nielsen MS. Klinger SC, et al. Among authors: petersen cm. J Cell Sci. 2011 Apr 1;124(Pt 7):1095-105. doi: 10.1242/jcs.072538. Epub 2011 Mar 8. J Cell Sci. 2011. PMID: 21385844 Free article.
SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.
Glerup S, Lume M, Olsen D, Nyengaard JR, Vaegter CB, Gustafsen C, Christensen EI, Kjolby M, Hay-Schmidt A, Bender D, Madsen P, Saarma M, Nykjaer A, Petersen CM. Glerup S, et al. Among authors: petersen cm. Cell Rep. 2013 Jan 31;3(1):186-99. doi: 10.1016/j.celrep.2012.12.011. Epub 2013 Jan 17. Cell Rep. 2013. PMID: 23333276 Free article.
Functional organization of the sortilin Vps10p domain.
Westergaard UB, Sørensen ES, Hermey G, Nielsen MS, Nykjaer A, Kirkegaard K, Jacobsen C, Gliemann J, Madsen P, Petersen CM. Westergaard UB, et al. Among authors: petersen cm. J Biol Chem. 2004 Nov 26;279(48):50221-9. doi: 10.1074/jbc.M408873200. Epub 2004 Sep 10. J Biol Chem. 2004. PMID: 15364913 Free article.
Sortilin is essential for proNGF-induced neuronal cell death.
Nykjaer A, Lee R, Teng KK, Jansen P, Madsen P, Nielsen MS, Jacobsen C, Kliemannel M, Schwarz E, Willnow TE, Hempstead BL, Petersen CM. Nykjaer A, et al. Among authors: petersen cm. Nature. 2004 Feb 26;427(6977):843-8. doi: 10.1038/nature02319. Nature. 2004. PMID: 14985763
The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-derived growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand.
Gliemann J, Hermey G, Nykjaer A, Petersen CM, Jacobsen C, Andreasen PA. Gliemann J, et al. Among authors: petersen cm. Biochem J. 2004 Jul 1;381(Pt 1):203-12. doi: 10.1042/BJ20040149. Biochem J. 2004. PMID: 15053742 Free PMC article.
Different motifs regulate trafficking of SorCS1 isoforms.
Nielsen MS, Keat SJ, Hamati JW, Madsen P, Gutzmann JJ, Engelsberg A, Pedersen KM, Gustafsen C, Nykjaer A, Gliemann J, Hermans-Borgmeyer I, Kuhl D, Petersen CM, Hermey G. Nielsen MS, et al. Among authors: petersen cm. Traffic. 2008 Jun;9(6):980-94. doi: 10.1111/j.1600-0854.2008.00731.x. Epub 2008 Feb 27. Traffic. 2008. PMID: 18315530 Free article.
118 results