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Functional and toxicological consequences of metabolic bioactivation of methapyrilene via thiophene S-oxidation: Induction of cell defence, apoptosis and hepatic necrosis.
Mercer AE, Regan SL, Hirst CM, Graham EE, Antoine DJ, Benson CA, Williams DP, Foster J, Kenna JG, Park BK. Mercer AE, et al. Among authors: antoine dj. Toxicol Appl Pharmacol. 2009 Sep 15;239(3):297-305. doi: 10.1016/j.taap.2009.05.027. Epub 2009 Jun 10. Toxicol Appl Pharmacol. 2009. PMID: 19523481
RETRACTED: Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity.
Antoine DJ, Jenkins RE, Dear JW, Williams DP, McGill MR, Sharpe MR, Craig DG, Simpson KJ, Jaeschke H, Park BK. Antoine DJ, et al. J Hepatol. 2012 May;56(5):1070-1079. doi: 10.1016/j.jhep.2011.12.019. Epub 2012 Jan 17. J Hepatol. 2012. Retraction in: J Hepatol. 2020 Nov;73(5):1297. doi: 10.1016/j.jhep.2020.08.022 PMID: 22266604 Free PMC article. Retracted.
Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.
Woolbright BL, Dorko K, Antoine DJ, Clarke JI, Gholami P, Li F, Kumer SC, Schmitt TM, Forster J, Fan F, Jenkins RE, Park BK, Hagenbuch B, Olyaee M, Jaeschke H. Woolbright BL, et al. Among authors: antoine dj. Toxicol Appl Pharmacol. 2015 Mar 15;283(3):168-77. doi: 10.1016/j.taap.2015.01.015. Epub 2015 Jan 28. Toxicol Appl Pharmacol. 2015. PMID: 25636263 Free PMC article.
Role of reactive metabolites in drug-induced hepatotoxicity.
Srivastava A, Maggs JL, Antoine DJ, Williams DP, Smith DA, Park BK. Srivastava A, et al. Among authors: antoine dj. Handb Exp Pharmacol. 2010;(196):165-94. doi: 10.1007/978-3-642-00663-0_7. Handb Exp Pharmacol. 2010. PMID: 20020263 Review.
Serum microRNA biomarkers for drug-induced liver injury.
Starkey Lewis PJ, Merz M, Couttet P, Grenet O, Dear J, Antoine DJ, Goldring C, Park BK, Moggs JG. Starkey Lewis PJ, et al. Among authors: antoine dj. Clin Pharmacol Ther. 2012 Sep;92(3):291-3. doi: 10.1038/clpt.2012.101. Epub 2012 Jul 25. Clin Pharmacol Ther. 2012. PMID: 22828715 Review.
143 results