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Page 1
Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.
Saarikangas J, Mattila PK, Varjosalo M, Bovellan M, Hakanen J, Calzada-Wack J, Tost M, Jennen L, Rathkolb B, Hans W, Horsch M, Hyvönen ME, Perälä N, Fuchs H, Gailus-Durner V, Esposito I, Wolf E, de Angelis MH, Frilander MJ, Savilahti H, Sariola H, Sainio K, Lehtonen S, Taipale J, Salminen M, Lappalainen P. Saarikangas J, et al. Among authors: hyvonen me. J Cell Sci. 2011 Apr 15;124(Pt 8):1245-55. doi: 10.1242/jcs.082610. Epub 2011 Mar 15. J Cell Sci. 2011. PMID: 21406566
Lipid phosphatase SHIP2 downregulates insulin signalling in podocytes.
Hyvönen ME, Saurus P, Wasik A, Heikkilä E, Havana M, Trokovic R, Saleem M, Holthöfer H, Lehtonen S. Hyvönen ME, et al. Mol Cell Endocrinol. 2010 Oct 26;328(1-2):70-9. doi: 10.1016/j.mce.2010.07.016. Epub 2010 Jul 21. Mol Cell Endocrinol. 2010. PMID: 20654688
Ezrin is down-regulated in diabetic kidney glomeruli and regulates actin reorganization and glucose uptake via GLUT1 in cultured podocytes.
Wasik AA, Koskelainen S, Hyvönen ME, Musante L, Lehtonen E, Koskenniemi K, Tienari J, Vaheri A, Kerjaschki D, Szalay C, Révész C, Varmanen P, Nyman TA, Hamar P, Holthöfer H, Lehtonen S. Wasik AA, et al. Among authors: hyvonen me. Am J Pathol. 2014 Jun;184(6):1727-39. doi: 10.1016/j.ajpath.2014.03.002. Epub 2014 Apr 13. Am J Pathol. 2014. PMID: 24726496
Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway.
Saurus P, Kuusela S, Lehtonen E, Hyvönen ME, Ristola M, Fogarty CL, Tienari J, Lassenius MI, Forsblom C, Lehto M, Saleem MA, Groop PH, Holthöfer H, Lehtonen S. Saurus P, et al. Among authors: hyvonen me. Cell Death Dis. 2015 May 7;6(5):e1752. doi: 10.1038/cddis.2015.125. Cell Death Dis. 2015. PMID: 25950482 Free PMC article.
CD2AP is associated with end-stage renal disease in patients with type 1 diabetes.
Hyvönen ME, Ihalmo P, Sandholm N, Stavarachi M, Forsblom C, McKnight AJ, Lajer M, Maestroni A, Lewis G, Tarnow L, Maestroni S, Zerbini G, Parving HH, Maxwell AP, Groop PH, Lehtonen S. Hyvönen ME, et al. Acta Diabetol. 2013 Dec;50(6):887-97. doi: 10.1007/s00592-013-0475-9. Epub 2013 May 17. Acta Diabetol. 2013. PMID: 23681557
MiniMed 780G™ in 2- to 6-Year-Old Children: Safety and Clinical Outcomes After the First 12 Weeks.
Pulkkinen MA, Varimo TJ, Hakonen ET, Harsunen MH, Hyvönen ME, Janér JN, Kiiveri SM, Laakkonen HM, Laakso SM, Wehkalampi K, Hero MT, Miettinen PJ, Tuomaala AK. Pulkkinen MA, et al. Among authors: hyvonen me. Diabetes Technol Ther. 2023 Feb;25(2):100-107. doi: 10.1089/dia.2022.0313. Epub 2022 Dec 30. Diabetes Technol Ther. 2023. PMID: 36511831 Clinical Trial.
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