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Page 1
Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.
Saarikangas J, Mattila PK, Varjosalo M, Bovellan M, Hakanen J, Calzada-Wack J, Tost M, Jennen L, Rathkolb B, Hans W, Horsch M, Hyvönen ME, Perälä N, Fuchs H, Gailus-Durner V, Esposito I, Wolf E, de Angelis MH, Frilander MJ, Savilahti H, Sariola H, Sainio K, Lehtonen S, Taipale J, Salminen M, Lappalainen P. Saarikangas J, et al. Among authors: lehtonen s. J Cell Sci. 2011 Apr 15;124(Pt 8):1245-55. doi: 10.1242/jcs.082610. Epub 2011 Mar 15. J Cell Sci. 2011. PMID: 21406566
The R-Ras interaction partner ORP3 regulates cell adhesion.
Lehto M, Mäyränpää MI, Pellinen T, Ihalmo P, Lehtonen S, Kovanen PT, Groop PH, Ivaska J, Olkkonen VM. Lehto M, et al. Among authors: lehtonen s. J Cell Sci. 2008 Mar 1;121(Pt 5):695-705. doi: 10.1242/jcs.016964. Epub 2008 Feb 12. J Cell Sci. 2008. PMID: 18270267
Lipid phosphatase SHIP2 downregulates insulin signalling in podocytes.
Hyvönen ME, Saurus P, Wasik A, Heikkilä E, Havana M, Trokovic R, Saleem M, Holthöfer H, Lehtonen S. Hyvönen ME, et al. Among authors: lehtonen s. Mol Cell Endocrinol. 2010 Oct 26;328(1-2):70-9. doi: 10.1016/j.mce.2010.07.016. Epub 2010 Jul 21. Mol Cell Endocrinol. 2010. PMID: 20654688
CD2AP is associated with end-stage renal disease in patients with type 1 diabetes.
Hyvönen ME, Ihalmo P, Sandholm N, Stavarachi M, Forsblom C, McKnight AJ, Lajer M, Maestroni A, Lewis G, Tarnow L, Maestroni S, Zerbini G, Parving HH, Maxwell AP, Groop PH, Lehtonen S. Hyvönen ME, et al. Among authors: lehtonen s. Acta Diabetol. 2013 Dec;50(6):887-97. doi: 10.1007/s00592-013-0475-9. Epub 2013 May 17. Acta Diabetol. 2013. PMID: 23681557
Ezrin is down-regulated in diabetic kidney glomeruli and regulates actin reorganization and glucose uptake via GLUT1 in cultured podocytes.
Wasik AA, Koskelainen S, Hyvönen ME, Musante L, Lehtonen E, Koskenniemi K, Tienari J, Vaheri A, Kerjaschki D, Szalay C, Révész C, Varmanen P, Nyman TA, Hamar P, Holthöfer H, Lehtonen S. Wasik AA, et al. Among authors: lehtonen s, lehtonen e. Am J Pathol. 2014 Jun;184(6):1727-39. doi: 10.1016/j.ajpath.2014.03.002. Epub 2014 Apr 13. Am J Pathol. 2014. PMID: 24726496
Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway.
Saurus P, Kuusela S, Lehtonen E, Hyvönen ME, Ristola M, Fogarty CL, Tienari J, Lassenius MI, Forsblom C, Lehto M, Saleem MA, Groop PH, Holthöfer H, Lehtonen S. Saurus P, et al. Among authors: lehtonen s, lehtonen e. Cell Death Dis. 2015 May 7;6(5):e1752. doi: 10.1038/cddis.2015.125. Cell Death Dis. 2015. PMID: 25950482 Free PMC article.
235 results