Luo L - Search Results

1

Biochemical characterization of human HIF hydroxylases using HIF protein substrates that contain all three hydroxylation sites.

Pappalardi MB, McNulty DE, Martin JD, Fisher KE, Jiang Y, Burns MC, Zhao H, Ho T, Sweitzer S, Schwartz B, Annan RS, Copeland RA, Tummino PJ, Luo L. Pappalardi MB, et al. Among authors: luo l. Biochem J. 2011 Jun 1;436(2):363-9. doi: 10.1042/BJ20101201. Biochem J. 2011. PMID: 21410436

2

Biochemical characterization of human prolyl hydroxylase domain protein 2 variants associated with erythrocytosis.

Pappalardi MB, Martin JD, Jiang Y, Burns MC, Zhao H, Ho T, Sweitzer S, Lor L, Schwartz B, Duffy K, Gontarek R, Tummino PJ, Copeland RA, Luo L. Pappalardi MB, et al. Among authors: luo l. Biochemistry. 2008 Oct 28;47(43):11165-7. doi: 10.1021/bi801624f. Epub 2008 Oct 4. Biochemistry. 2008. PMID: 18834144

3

Effects of oncogenic p110alpha subunit mutations on the lipid kinase activity of phosphoinositide 3-kinase.

Carson JD, Van Aller G, Lehr R, Sinnamon RH, Kirkpatrick RB, Auger KR, Dhanak D, Copeland RA, Gontarek RR, Tummino PJ, Luo L. Carson JD, et al. Among authors: luo l. Biochem J. 2008 Jan 15;409(2):519-24. doi: 10.1042/BJ20070681. Biochem J. 2008. PMID: 17877460

4

Epigallocatechin gallate (EGCG), a major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor.

Van Aller GS, Carson JD, Tang W, Peng H, Zhao L, Copeland RA, Tummino PJ, Luo L. Van Aller GS, et al. Among authors: luo l. Biochem Biophys Res Commun. 2011 Mar 11;406(2):194-9. doi: 10.1016/j.bbrc.2011.02.010. Epub 2011 Feb 15. Biochem Biophys Res Commun. 2011. PMID: 21300025

5

A method for determining intracellular concentrations of enzyme substrates from a combination of competitive inhibition and mutagenesis studies.

Copeland RA, Luo L, Auger KR, Huang PS. Copeland RA, et al. Among authors: luo l. Anal Biochem. 2005 Feb 15;337(2):351-3. doi: 10.1016/j.ab.2004.10.010. Anal Biochem. 2005. PMID: 15691518 No abstract available.

6

An assay for Fe(II)/2-oxoglutarate-dependent dioxygenases by enzyme-coupled detection of succinate formation.

Luo L, Pappalardi MB, Tummino PJ, Copeland RA, Fraser ME, Grzyska PK, Hausinger RP. Luo L, et al. Anal Biochem. 2006 Jun 1;353(1):69-74. doi: 10.1016/j.ab.2006.03.033. Epub 2006 Apr 19. Anal Biochem. 2006. PMID: 16643838

7

ATP-competitive inhibitors of the mitotic kinesin KSP that function via an allosteric mechanism.

Luo L, Parrish CA, Nevins N, McNulty DE, Chaudhari AM, Carson JD, Sudakin V, Shaw AN, Lehr R, Zhao H, Sweitzer S, Lad L, Wood KW, Sakowicz R, Annan RS, Huang PS, Jackson JR, Dhanak D, Copeland RA, Auger KR. Luo L, et al. Nat Chem Biol. 2007 Nov;3(11):722-6. doi: 10.1038/nchembio.2007.34. Epub 2007 Oct 7. Nat Chem Biol. 2007. PMID: 17922005

8

Characterization of an exosite binding inhibitor of matrix metalloproteinase 13.

Gooljarsingh LT, Lakdawala A, Coppo F, Luo L, Fields GB, Tummino PJ, Gontarek RR. Gooljarsingh LT, et al. Among authors: luo l. Protein Sci. 2008 Jan;17(1):66-71. doi: 10.1110/ps.073130208. Epub 2007 Nov 27. Protein Sci. 2008. PMID: 18042679 Free PMC article.

9

Conformation-dependent ligand regulation of ATP hydrolysis by human KSP: activation of basal hydrolysis and inhibition of microtubule-stimulated hydrolysis by a single, small molecule modulator.

Luo L, Carson JD, Molnar KS, Tuske SJ, Coales SJ, Hamuro Y, Sung CM, Sudakin V, Auger KR, Dhanak D, Jackson JR, Huang PS, Tummino PJ, Copeland RA. Luo L, et al. J Am Chem Soc. 2008 Jun 18;130(24):7584-91. doi: 10.1021/ja710889h. Epub 2008 May 21. J Am Chem Soc. 2008. PMID: 18491908

10

Characterization of PI3K class IA isoforms with regulatory subunit p55alpha using a scintillation proximity assay.

Van Aller GS, Carson JD, Fernandes C, Lehr R, Sinnamon RH, Kirkpatrick RB, Tummino PJ, Luo L. Van Aller GS, et al. Among authors: luo l. Anal Biochem. 2008 Dec 15;383(2):311-5. doi: 10.1016/j.ab.2008.08.037. Epub 2008 Sep 10. Anal Biochem. 2008. PMID: 18814837

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