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DHODH modulates transcriptional elongation in the neural crest and melanoma.
White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahl PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, Granter S, Young RA, Morrison S, Wheeler GN, Zon LI. White RM, et al. Among authors: chen f. Nature. 2011 Mar 24;471(7339):518-22. doi: 10.1038/nature09882. Nature. 2011. PMID: 21430780 Free PMC article.
A new highly penetrant form of obesity due to deletions on chromosome 16p11.2.
Walters RG, Jacquemont S, Valsesia A, de Smith AJ, Martinet D, Andersson J, Falchi M, Chen F, Andrieux J, Lobbens S, Delobel B, Stutzmann F, El-Sayed Moustafa JS, Chèvre JC, Lecoeur C, Vatin V, Bouquillon S, Buxton JL, Boute O, Holder-Espinasse M, Cuisset JM, Lemaitre MP, Ambresin AE, Brioschi A, Gaillard M, Giusti V, Fellmann F, Ferrarini A, Hadjikhani N, Campion D, Guilmatre A, Goldenberg A, Calmels N, Mandel JL, Le Caignec C, David A, Isidor B, Cordier MP, Dupuis-Girod S, Labalme A, Sanlaville D, Béri-Dexheimer M, Jonveaux P, Leheup B, Ounap K, Bochukova EG, Henning E, Keogh J, Ellis RJ, Macdermot KD, van Haelst MM, Vincent-Delorme C, Plessis G, Touraine R, Philippe A, Malan V, Mathieu-Dramard M, Chiesa J, Blaumeiser B, Kooy RF, Caiazzo R, Pigeyre M, Balkau B, Sladek R, Bergmann S, Mooser V, Waterworth D, Reymond A, Vollenweider P, Waeber G, Kurg A, Palta P, Esko T, Metspalu A, Nelis M, Elliott P, Hartikainen AL, McCarthy MI, Peltonen L, Carlsson L, Jacobson P, Sjöström L, Huang N, Hurles ME, O'Rahilly S, Farooqi IS, Männik K, Jarvelin MR, Pattou F, Meyre D, Walley AJ, Coin LJ, Blakemore AI, Froguel P, Beckmann JS. Walters RG, et al. Among authors: chen f. Nature. 2010 Feb 4;463(7281):671-5. doi: 10.1038/nature08727. Nature. 2010. PMID: 20130649 Free PMC article.
Nonacademic predictors of China medical licensing examination.
Sun J, Xie Y, Zhang N, Cheng J, Wang M, Zhang B, Zhu W, Zhang H, Qiu S, Xu X, Yu Y, Han T, Geng Z, Liao W, Gao B, Qin W, Liu F, Liang M, Xu Q, Fu J, Xu J, Liu M, Zhang P, Li W, Shi D, Wang C, Zuo XN, Zhang Q, Chen F, Li J, Yan Z, Shen W, Miao Y, Xian J, Zhang L, Xu K, Ye Z, Zhang J, Cui G, Yu C; CHIMGEN Consortium. Sun J, et al. Among authors: chen f. BMC Med Educ. 2025 Jan 14;25(1):65. doi: 10.1186/s12909-025-06652-7. BMC Med Educ. 2025. PMID: 39810155
Catalytic-independent functions of the Integrator-PP2A complex (INTAC) confer sensitivity to BET inhibition.
Fan P, Shang XY, Song A, Chen S, Mao RY, Ma J, Chen J, Wang Z, Zheng H, Tao B, Hong L, Liu J, Xu W, Jiang W, Shen H, Zhang Q, Yang H, Meng XM, Lan F, Cheng J, Xu C, Zhang P, Jiang H, Chen FX. Fan P, et al. Among authors: chen fx. Nat Chem Biol. 2025 Jan 14. doi: 10.1038/s41589-024-01807-x. Online ahead of print. Nat Chem Biol. 2025. PMID: 39809894
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