Langdon WY - Search Results

1

Incidence of c-Cbl mutations in human acute myeloid leukaemias in an Australian patient cohort.

Ghassemifar R, Thien CB, Finlayson J, Joske D, Cull GM, Augustson B, Langdon WY. Ghassemifar R, et al. Among authors: langdon wy. Pathology. 2011 Apr;43(3):261-5. doi: 10.1097/PAT.0b013e328343ca4b. Pathology. 2011. PMID: 21436637

2

Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor.

Oksvold MP, Thien CB, Widerberg J, Chantry A, Huitfeldt HS, Langdon WY. Oksvold MP, et al. Among authors: langdon wy. Oncogene. 2003 Nov 20;22(52):8509-18. doi: 10.1038/sj.onc.1207117. Oncogene. 2003. PMID: 14627991

3

Negative regulation of PTK signalling by Cbl proteins.

Thien CB, Langdon WY. Thien CB, et al. Among authors: langdon wy. Growth Factors. 2005 Jun;23(2):161-7. doi: 10.1080/08977190500153763. Growth Factors. 2005. PMID: 16019438 Review.

4

c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses.

Thien CB, Langdon WY. Thien CB, et al. Among authors: langdon wy. Biochem J. 2005 Oct 15;391(Pt 2):153-66. doi: 10.1042/BJ20050892. Biochem J. 2005. PMID: 16212556 Free PMC article. Review.

5

Loss of c-Cbl E3 ubiquitin ligase activity enhances the development of myeloid leukemia in FLT3-ITD mutant mice.

Taylor SJ, Thien CB, Dagger SA, Duyvestyn JM, Grove CS, Lee BH, Gilliland DG, Langdon WY. Taylor SJ, et al. Among authors: langdon wy. Exp Hematol. 2015 Mar;43(3):191-206.e1. doi: 10.1016/j.exphem.2014.11.009. Epub 2014 Dec 19. Exp Hematol. 2015. PMID: 25534201 Free article.

6

EGF receptor binding and transformation by v-cbl is ablated by the introduction of a loss-of-function mutation from the Caenorhabditis elegans sli-1 gene.

Thien CB, Langdon WY. Thien CB, et al. Among authors: langdon wy. Oncogene. 1997 May 8;14(18):2239-49. doi: 10.1038/sj.onc.1201193. Oncogene. 1997. PMID: 9174060

7

c-Cbl: a regulator of T cell receptor-mediated signalling.

Thien CB, Langdon WY. Thien CB, et al. Among authors: langdon wy. Immunol Cell Biol. 1998 Oct;76(5):473-82. doi: 10.1046/j.1440-1711.1998.00768.x. Immunol Cell Biol. 1998. PMID: 9797470 Review.

8

A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase.

Thien CB, Scaife RM, Papadimitriou JM, Murphy MA, Bowtell DD, Langdon WY. Thien CB, et al. Among authors: langdon wy. J Exp Med. 2003 Feb 17;197(4):503-13. doi: 10.1084/jem.20021498. J Exp Med. 2003. PMID: 12591907 Free PMC article.

9

Myeloid leukemia development in c-Cbl RING finger mutant mice is dependent on FLT3 signaling.

Rathinam C, Thien CB, Flavell RA, Langdon WY. Rathinam C, et al. Among authors: langdon wy. Cancer Cell. 2010 Oct 19;18(4):341-52. doi: 10.1016/j.ccr.2010.09.008. Cancer Cell. 2010. PMID: 20951944 Free article.

10

The two major sites of cbl tyrosine phosphorylation in abl-transformed cells select the crkL SH2 domain.

Andoniou CE, Thien CB, Langdon WY. Andoniou CE, et al. Among authors: langdon wy. Oncogene. 1996 May 2;12(9):1981-9. Oncogene. 1996. PMID: 8649859

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