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209 results

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Mitotic lethality prevents inflammation.
Zierhut C, Villunger A. Zierhut C, et al. Among authors: villunger a. Nat Cell Biol. 2025 Jan;27(1):7-8. doi: 10.1038/s41556-024-01529-1. Nat Cell Biol. 2025. PMID: 39809996 No abstract available.
Global analysis of endogenous protein disorder in cells.
Zhang S, Owyong TC, Sanislav O, Englmaier L, Sui X, Wang G, Greening DW, Williamson NA, Villunger A, White JM, Heras B, Wong WWH, Fisher PR, Hong Y. Zhang S, et al. Among authors: villunger a. Nat Methods. 2025 Jan;22(1):124-134. doi: 10.1038/s41592-024-02507-z. Epub 2024 Nov 25. Nat Methods. 2025. PMID: 39587358
Discovery of nostatin A, an azole-containing proteusin with prominent cytostatic and pro-apoptotic activity.
Delawská K, Hájek J, Voráčová K, Kuzma M, Mareš J, Vicková K, Kádek A, Tučková D, Gallob F, Divoká P, Moos M, Opekar S, Koch L, Saurav K, Sedlák D, Novák P, Urajová P, Dean J, Gažák R, Niedermeyer TJH, Kameník Z, Šimek P, Villunger A, Hrouzek P. Delawská K, et al. Among authors: villunger a. Org Biomol Chem. 2025 Jan 2;23(2):449-460. doi: 10.1039/d4ob01395f. Org Biomol Chem. 2025. PMID: 39576263 Free PMC article.
Caspase-2 kills cells with extra centrosomes.
Rizzotto D, Vigorito V, Rieder P, Gallob F, Moretta GM, Soratroi C, Riley JS, Bellutti F, Veli SL, Mattivi A, Lohmüller M, Herzog S, Bornhauser BC, Jacotot ED, Villunger A, Fava LL. Rizzotto D, et al. Among authors: villunger a. Sci Adv. 2024 Nov;10(44):eado6607. doi: 10.1126/sciadv.ado6607. Epub 2024 Oct 30. Sci Adv. 2024. PMID: 39475598 Free PMC article.
Cyclin C promotes development and progression of B-cell acute lymphoblastic leukemia by counteracting p53-mediated stress responses.
Trifinopoulos J, List J, Klampfl T, Klein K, Prchal-Murphy M, Witalisz-Siepracka A, Bellutti F, Fava LL, Heller G, Stummer S, Testori P, Den Boer ML, Boer JM, Marinovic S, Hoermann G, Walter W, Villunger A, Sicinski P, Sexl V, Gotthardt D. Trifinopoulos J, et al. Among authors: villunger a. Haematologica. 2024 Oct 10. doi: 10.3324/haematol.2024.285701. Online ahead of print. Haematologica. 2024. PMID: 39385738 Free article.
Amplified centrosomes-more than just a threat.
Kiermaier E, Stötzel I, Schapfl MA, Villunger A. Kiermaier E, et al. Among authors: villunger a. EMBO Rep. 2024 Oct;25(10):4153-4167. doi: 10.1038/s44319-024-00260-0. Epub 2024 Sep 16. EMBO Rep. 2024. PMID: 39285247 Free PMC article. Review.
Extra centrosomes delay DNA damage-driven tumorigenesis.
Braun VZ, Karbon G, Schuler F, Schapfl MA, Weiss JG, Petermann PY, Spierings DCJ, Tijhuis AE, Foijer F, Labi V, Villunger A. Braun VZ, et al. Among authors: villunger a. Sci Adv. 2024 Mar 29;10(13):eadk0564. doi: 10.1126/sciadv.adk0564. Epub 2024 Mar 29. Sci Adv. 2024. PMID: 38552015 Free PMC article.
209 results