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Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway.
Awazawa M, Ueki K, Inabe K, Yamauchi T, Kubota N, Kaneko K, Kobayashi M, Iwane A, Sasako T, Okazaki Y, Ohsugi M, Takamoto I, Yamashita S, Asahara H, Akira S, Kasuga M, Kadowaki T. Awazawa M, et al. Among authors: okazaki y. Cell Metab. 2011 Apr 6;13(4):401-412. doi: 10.1016/j.cmet.2011.02.010. Cell Metab. 2011. PMID: 21459325 Free article.
Role of uncoupling protein-2 up-regulation and triglyceride accumulation in impaired glucose-stimulated insulin secretion in a beta-cell lipotoxicity model overexpressing sterol regulatory element-binding protein-1c.
Yamashita T, Eto K, Okazaki Y, Yamashita S, Yamauchi T, Sekine N, Nagai R, Noda M, Kadowaki T. Yamashita T, et al. Among authors: okazaki y. Endocrinology. 2004 Aug;145(8):3566-77. doi: 10.1210/en.2003-1602. Epub 2004 Apr 1. Endocrinology. 2004. PMID: 15059954
Class IA phosphatidylinositol 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms.
Kaneko K, Ueki K, Takahashi N, Hashimoto S, Okamoto M, Awazawa M, Okazaki Y, Ohsugi M, Inabe K, Umehara T, Yoshida M, Kakei M, Kitamura T, Luo J, Kulkarni RN, Kahn CR, Kasai H, Cantley LC, Kadowaki T. Kaneko K, et al. Among authors: okazaki y. Cell Metab. 2010 Dec 1;12(6):619-32. doi: 10.1016/j.cmet.2010.11.005. Cell Metab. 2010. PMID: 21109194 Free PMC article.
Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance.
Kobayashi N, Ueki K, Okazaki Y, Iwane A, Kubota N, Ohsugi M, Awazawa M, Kobayashi M, Sasako T, Kaneko K, Suzuki M, Nishikawa Y, Hara K, Yoshimura K, Koshima I, Goyama S, Murakami K, Sasaki J, Nagai R, Kurokawa M, Sasaki T, Kadowaki T. Kobayashi N, et al. Among authors: okazaki y. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5753-8. doi: 10.1073/pnas.1016430108. Epub 2011 Mar 21. Proc Natl Acad Sci U S A. 2011. PMID: 21436039 Free PMC article.
[Japan Diabetes Outcome Intervention Trial 3].
Okazaki Y, Ueki K. Okazaki Y, et al. Nihon Rinsho. 2010 Nov;68 Suppl 9:87-90. Nihon Rinsho. 2010. PMID: 21667471 Clinical Trial. Japanese. No abstract available.
Design of and rationale for the Japan Diabetes Optimal Integrated Treatment study for 3 major risk factors of cardiovascular diseases (J-DOIT3): a multicenter, open-label, randomized, parallel-group trial.
Ueki K, Sasako T, Kato M, Okazaki Y, Okahata S, Katsuyama H, Haraguchi M, Morita A, Ohashi K, Hara K, Morise A, Izumi K, Ohashi Y, Noda M, Kadowaki T; J-DOIT3 Study Group. Ueki K, et al. Among authors: okazaki y. BMJ Open Diabetes Res Care. 2016 Jan 25;4(1):e000123. doi: 10.1136/bmjdrc-2015-000123. eCollection 2016. BMJ Open Diabetes Res Care. 2016. PMID: 26843962 Free PMC article.
1,710 results