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Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome.
Sharp FA, Ruane D, Claass B, Creagh E, Harris J, Malyala P, Singh M, O'Hagan DT, Pétrilli V, Tschopp J, O'Neill LA, Lavelle EC. Sharp FA, et al. Among authors: tschopp j. Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):870-5. doi: 10.1073/pnas.0804897106. Epub 2009 Jan 12. Proc Natl Acad Sci U S A. 2009. PMID: 19139407 Free PMC article.
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence.
Gross O, Poeck H, Bscheider M, Dostert C, Hannesschläger N, Endres S, Hartmann G, Tardivel A, Schweighoffer E, Tybulewicz V, Mocsai A, Tschopp J, Ruland J. Gross O, et al. Among authors: tschopp j. Nature. 2009 May 21;459(7245):433-6. doi: 10.1038/nature07965. Epub 2009 Apr 1. Nature. 2009. PMID: 19339971
623 results