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Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor.
Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski TF, López JR, Beam KG, Allen PD. Eltit JM, et al. Among authors: pessah in. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7923-8. doi: 10.1073/pnas.1119207109. Epub 2012 Apr 30. Proc Natl Acad Sci U S A. 2012. PMID: 22547813 Free PMC article.
Amino acid residues Gln4020 and Lys4021 of the ryanodine receptor type 1 are required for activation by 4-chloro-m-cresol.
Fessenden JD, Feng W, Pessah IN, Allen PD. Fessenden JD, et al. Among authors: pessah in. J Biol Chem. 2006 Jul 28;281(30):21022-21031. doi: 10.1074/jbc.M600670200. Epub 2006 May 31. J Biol Chem. 2006. PMID: 16737973 Free article.
We previously showed that a 173-amino acid segment of RyR1 (residues 4007-4180) is required for channel activation by 4-CmC (Fessenden, J. D., Perez, C. F., Goth, S., Pessah, I. N., and Allen, P. D. (2003) J. Biol. Chem. 278, 28727-28735). In the present study, we u …
We previously showed that a 173-amino acid segment of RyR1 (residues 4007-4180) is required for channel activation by 4-CmC (Fessenden, J. D …
255 results