Weaver JL - Search Results

1

Effects of modulating in vivo nitric oxide production on the incidence and severity of PDE4 inhibitor-induced vascular injury in Sprague-Dawley rats.

Sheth CM, Enerson BE, Peters D, Lawton MP, Weaver JL. Sheth CM, et al. Among authors: weaver jl. Toxicol Sci. 2011 Jul;122(1):7-15. doi: 10.1093/toxsci/kfr082. Epub 2011 Apr 16. Toxicol Sci. 2011. PMID: 21498876

2

Evaluation of the Tg.AC assay: specificity testing with three noncarcinogenic pharmaceuticals that induce selected stress gene promoters in vitro and the inhibitory effects of solvent components.

Thompson KL, Rosenzweig BA, Weaver JL, Zhang J, Lin KK, Sistare FD. Thompson KL, et al. Among authors: weaver jl. Toxicol Sci. 2003 Aug;74(2):271-8. doi: 10.1093/toxsci/kfg141. Epub 2003 May 28. Toxicol Sci. 2003. PMID: 12773758

3

Isoproterenol-induced cardiotoxicity in sprague-dawley rats: correlation of reversible and irreversible myocardial injury with release of cardiac troponin T and roles of iNOS in myocardial injury.

Zhang J, Knapton A, Lipshultz SE, Weaver JL, Herman EH. Zhang J, et al. Among authors: weaver jl. Toxicol Pathol. 2008 Feb;36(2):277-8. doi: 10.1177/0192623307313010. Epub 2008 Mar 18. Toxicol Pathol. 2008. PMID: 18349426

4

Histopathology of vascular injury in Sprague-Dawley rats treated with phosphodiesterase IV inhibitor SCH 351591 or SCH 534385.

Zhang J, Snyder RD, Herman EH, Knapton A, Honchel R, Miller T, Espandiari P, Goodsaid FM, Rosenblum IY, Hanig JP, Sistare FD, Weaver JL. Zhang J, et al. Among authors: weaver jl. Toxicol Pathol. 2008 Oct;36(6):827-39. doi: 10.1177/0192623308322308. Epub 2008 Sep 5. Toxicol Pathol. 2008. PMID: 18776163

5

Biomarkers in peripheral blood associated with vascular injury in Sprague-Dawley rats treated with the phosphodiesterase IV inhibitors SCH 351591 or SCH 534385.

Weaver JL, Snyder R, Knapton A, Herman EH, Honchel R, Miller T, Espandiari P, Smith R, Gu YZ, Goodsaid FM, Rosenblum IY, Sistare FD, Zhang J, Hanig J. Weaver JL, et al. Toxicol Pathol. 2008 Oct;36(6):840-9. doi: 10.1177/0192623308322310. Epub 2008 Sep 5. Toxicol Pathol. 2008. PMID: 18776166

6

Early events in vascular injury in the rat induced by the phosphodiesterase IV inhibitor SCH 351591.

Weaver JL, Zhang J, Knapton A, Miller T, Espandiari P, Smith R, Gu YZ, Snyder RD. Weaver JL, et al. Toxicol Pathol. 2010 Aug;38(5):738-44. doi: 10.1177/0192623310374331. Epub 2010 Jun 28. Toxicol Pathol. 2010. PMID: 20585143

7

The role of eNOS phosphorylation in causing drug-induced vascular injury.

Tobin GA, Zhang J, Goodwin D, Stewart S, Xu L, Knapton A, González C, Bancos S, Zhang L, Lawton MP, Enerson BE, Weaver JL. Tobin GA, et al. Among authors: weaver jl. Toxicol Pathol. 2014 Jun;42(4):709-24. doi: 10.1177/0192623314522885. Epub 2014 Apr 3. Toxicol Pathol. 2014. PMID: 24705881

8

Nonclinical safety biomarkers of drug-induced vascular injury: current status and blueprint for the future.

Mikaelian I, Cameron M, Dalmas DA, Enerson BE, Gonzalez RJ, Guionaud S, Hoffmann PK, King NM, Lawton MP, Scicchitano MS, Smith HW, Thomas RA, Weaver JL, Zabka TS; Vascular Injury Working Group of the Predictive Safety Consortium. Mikaelian I, et al. Among authors: weaver jl. Toxicol Pathol. 2014 Jun;42(4):635-57. doi: 10.1177/0192623314525686. Epub 2014 Apr 28. Toxicol Pathol. 2014. PMID: 24777748

9

Scientific and Regulatory Policy Committee Points-to-consider Paper*: Drug-induced Vascular Injury Associated with Nonsmall Molecule Therapeutics in Preclinical Development: Part 2. Antisense Oligonucleotides.

Engelhardt JA, Fant P, Guionaud S, Henry SP, Leach MW, Louden C, Scicchitano MS, Weaver JL, Zabka TS, Frazier KS; Society of Toxicologic Pathology Vascular Injury Working Group. Engelhardt JA, et al. Among authors: weaver jl. Toxicol Pathol. 2015 Oct;43(7):935-44. doi: 10.1177/0192623315570341. Epub 2015 Feb 24. Toxicol Pathol. 2015. PMID: 25717082 Review.

10

BLT-Immune Humanized Mice as a Model for Nivolumab-Induced Immune-Mediated Adverse Events: Comparison of the NOG and NOG-EXL Strains.

Weaver JL, Zadrozny LM, Gabrielson K, Semple KM, Shea KI, Howard KE. Weaver JL, et al. Toxicol Sci. 2019 May 1;169(1):194-208. doi: 10.1093/toxsci/kfz045. Toxicol Sci. 2019. PMID: 30850839

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