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Page 1
Discovery of orally active, potent, and selective benzotriazole-based PTP1B inhibitors.
Patel D, Jain M, Shah SR, Bahekar R, Jadav P, Darji B, Siriki Y, Bandyopadhyay D, Joharapurkar A, Kshirsagar S, Patel H, Shaikh M, Sairam KV, Patel P. Patel D, et al. Among authors: patel h, patel p. ChemMedChem. 2011 Jun 6;6(6):1011-6. doi: 10.1002/cmdc.201100077. Epub 2011 Apr 19. ChemMedChem. 2011. PMID: 21506278 No abstract available.
Influence of acute and chronic kidney failure in rats on the disposition and pharmacokinetics of ZYAN1, a novel prolyl hydroxylase inhibitor, for the treatment of chronic kidney disease-induced anemia.
Patel H, Joharapurkar AA, Pandya VB, Patel VJ, Kshirsagar SG, Patel P, Gevriya B, Jain MR, Srinivas NR, Patel PR, Desai RC. Patel H, et al. Among authors: patel p, patel vj, patel pr. Xenobiotica. 2018 Jan;48(1):37-44. doi: 10.1080/00498254.2016.1278287. Epub 2017 Jan 19. Xenobiotica. 2018. PMID: 28042744
Discovery of a highly orally bioavailable c-5-[6-(4-Methanesulfonyloxyphenyl)hexyl]-2-methyl-1,3-dioxane-r-2-carboxylic acid as a potent hypoglycemic and hypolipidemic agent.
Pingali H, Jain M, Shah S, Basu S, Makadia P, Goswami A, Zaware P, Patil P, Godha A, Giri S, Goel A, Patel M, Patel H, Patel P. Pingali H, et al. Among authors: patel h, patel m, patel p. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5586-90. doi: 10.1016/j.bmcl.2008.08.112. Epub 2008 Sep 3. Bioorg Med Chem Lett. 2008. PMID: 18805005
Modulation of PPAR subtype selectivity. Part 2: Transforming PPARα/γ dual agonist into α selective PPAR agonist through bioisosteric modification.
Zaware P, Shah SR, Pingali H, Makadia P, Thube B, Pola S, Patel D, Priyadarshini P, Suthar D, Shah M, Jamili J, Sairam KV, Giri S, Patel L, Patel H, Sudani H, Patel H, Jain M, Patel P, Bahekar R. Zaware P, et al. Among authors: patel h, patel l, patel p, patel d. Bioorg Med Chem Lett. 2011 Jan 15;21(2):628-32. doi: 10.1016/j.bmcl.2010.12.032. Epub 2010 Dec 10. Bioorg Med Chem Lett. 2011. PMID: 21195611
Discovery of inhibitors of plasminogen activator inhibitor-1: structure-activity study of 5-nitro-2-phenoxybenzoic acid derivatives.
Pandya V, Jain M, Chakrabarti G, Soni H, Parmar B, Chaugule B, Patel J, Joshi J, Joshi N, Rath A, Raviya M, Shaikh M, Sairam KV, Patel H, Patel P. Pandya V, et al. Among authors: patel h, patel j, patel p. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5701-6. doi: 10.1016/j.bmcl.2011.08.031. Epub 2011 Aug 11. Bioorg Med Chem Lett. 2011. PMID: 21880486
Synthesis and structure-activity relationship of potent, selective and orally active anthranilamide-based factor Xa inhibitors: application of weakly basic sulfoximine group as novel S4 binding element.
Pandya V, Jain M, Chakrabarti G, Soni H, Parmar B, Chaugule B, Patel J, Jarag T, Joshi J, Joshi N, Rath A, Unadkat V, Sharma B, Ajani H, Kumar J, Sairam KV, Patel H, Patel P. Pandya V, et al. Among authors: patel h, patel j, patel p. Eur J Med Chem. 2012 Dec;58:136-52. doi: 10.1016/j.ejmech.2012.10.005. Epub 2012 Oct 16. Eur J Med Chem. 2012. PMID: 23124211
9,036 results