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635 results

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Page 1
FGF21 promotes metabolic homeostasis via white adipose and leptin in mice.
Véniant MM, Hale C, Helmering J, Chen MM, Stanislaus S, Busby J, Vonderfecht S, Xu J, Lloyd DJ. Véniant MM, et al. Among authors: hale c. PLoS One. 2012;7(7):e40164. doi: 10.1371/journal.pone.0040164. Epub 2012 Jul 6. PLoS One. 2012. PMID: 22792234 Free PMC article.
Molecular targeting of the GK-GKRP pathway in diabetes.
Hale C, Lloyd DJ, Pellacani A, Véniant MM. Hale C, et al. Expert Opin Ther Targets. 2015 Jan;19(1):129-39. doi: 10.1517/14728222.2014.965681. Epub 2014 Oct 17. Expert Opin Ther Targets. 2015. PMID: 25324018 Review.
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors.
Lloyd DJ, St Jean DJ Jr, Kurzeja RJ, Wahl RC, Michelsen K, Cupples R, Chen M, Wu J, Sivits G, Helmering J, Komorowski R, Ashton KS, Pennington LD, Fotsch C, Vazir M, Chen K, Chmait S, Zhang J, Liu L, Norman MH, Andrews KL, Bartberger MD, Van G, Galbreath EJ, Vonderfecht SL, Wang M, Jordan SR, Véniant MM, Hale C. Lloyd DJ, et al. Among authors: hale c. Nature. 2013 Dec 19;504(7480):437-40. doi: 10.1038/nature12724. Epub 2013 Nov 13. Nature. 2013. PMID: 24226772
The evolving systemic biomarker milieu in obese ZSF1 rat model of human cardiometabolic syndrome: Characterization of the model and cardioprotective effect of GDF15.
Stolina M, Luo X, Dwyer D, Han CY, Chen R, Zhang Y, Xiong Y, Chen Y, Yin J, Shkumatov A, Ason B, Hale C, Véniant MM. Stolina M, et al. Among authors: hale c. PLoS One. 2020 Aug 17;15(8):e0231234. doi: 10.1371/journal.pone.0231234. eCollection 2020. PLoS One. 2020. PMID: 32804947 Free PMC article.
Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice.
Xu J, Lloyd DJ, Hale C, Stanislaus S, Chen M, Sivits G, Vonderfecht S, Hecht R, Li YS, Lindberg RA, Chen JL, Jung DY, Zhang Z, Ko HJ, Kim JK, Véniant MM. Xu J, et al. Among authors: hale c. Diabetes. 2009 Jan;58(1):250-9. doi: 10.2337/db08-0392. Epub 2008 Oct 7. Diabetes. 2009. PMID: 18840786 Free PMC article.
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. Discovery of a novel tool compound for in vivo proof-of-concept.
Ashton KS, Andrews KL, Bryan MC, Chen J, Chen K, Chen M, Chmait S, Croghan M, Cupples R, Fotsch C, Helmering J, Jordan SR, Kurzeja RJ, Michelsen K, Pennington LD, Poon SF, Sivits G, Van G, Vonderfecht SL, Wahl RC, Zhang J, Lloyd DJ, Hale C, St Jean DJ Jr. Ashton KS, et al. Among authors: hale c. J Med Chem. 2014 Jan 23;57(2):309-24. doi: 10.1021/jm4016735. Epub 2014 Jan 9. J Med Chem. 2014. PMID: 24405172
635 results