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The effects of clobazam treatment in rats on the expression of genes and proteins encoding glucronosyltransferase 1A/2B (UGT1A/2B) and multidrug resistance-associated protein-2 (MRP2), and development of thyroid follicular cell hypertrophy.
Miyawaki I, Tamura A, Matsumoto I, Inada H, Kunimatsu T, Kimura J, Funabashi H. Miyawaki I, et al. Among authors: kimura j. Toxicol Appl Pharmacol. 2012 Dec 15;265(3):351-9. doi: 10.1016/j.taap.2012.09.003. Epub 2012 Sep 12. Toxicol Appl Pharmacol. 2012. PMID: 22982618
Oral administration of drugs with hypersensitivity potential induces germinal center hyperplasia in secondary lymphoid organ/tissue in Brown Norway rats, and this histological lesion is a promising candidate as a predictive biomarker for drug hypersensitivity occurrence in humans.
Tamura A, Miyawaki I, Yamada T, Kimura J, Funabashi H. Tamura A, et al. Among authors: kimura j. Toxicol Appl Pharmacol. 2013 Aug 15;271(1):30-40. doi: 10.1016/j.taap.2013.04.022. Epub 2013 May 5. Toxicol Appl Pharmacol. 2013. PMID: 23651737
Genotoxicity evaluation of benzene, di(2-ethylhexyl) phthalate, and trisodium ethylenediamine tetraacetic acid monohydrate using a combined rat comet/micronucleus assays.
Kitamoto S, Matsuyama R, Uematsu Y, Ogata K, Ota M, Yamada T, Miyata K, Kimura J, Funabashi H, Saito K. Kitamoto S, et al. Among authors: kimura j. Mutat Res Genet Toxicol Environ Mutagen. 2015 Jul;786-788:137-43. doi: 10.1016/j.mrgentox.2015.05.002. Epub 2015 May 8. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 26212304
Spontaneous Rhabdomyosarcoma in a Common Marmoset ( Callithrix jacchus ).
Tochitani T, Matsumoto I, Hoshino K, Toyosawa K, Kouchi M, Koujitani T, Kimura J, Funabashi H. Tochitani T, et al. Among authors: kimura j. J Toxicol Pathol. 2013 Jun;26(2):187-91. doi: 10.1293/tox.26.187. Epub 2013 Jul 10. J Toxicol Pathol. 2013. PMID: 23914060 Free PMC article.
1,257 results